Detailed information of TA system TA039809

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 673453..673981
• Replicon: chromosome
• Accession: NZ_AP024900
• Organism: Vibrio rarus strain LMG 23674

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCU56_RS03140
• Protein ID: WP_261874122.1
• Coordinates: 673453..673743 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU56_RS03145
• Protein ID: WP_261874123.1
• Coordinates: 673733..673981 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU56_RS03125	670146..671216	-	1071	WP_261874119.1	efflux RND transporter periplasmic adaptor subunit	-
OCU56_RS03130	671853..672326	+	474	WP_261874120.1	MarR family transcriptional regulator	-
OCU56_RS03135	672720..673316	+	597	WP_261874121.1	hypothetical protein	-
OCU56_RS03140	673453..673743	-	291	WP_261874122.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCU56_RS03145	673733..673981	-	249	WP_261874123.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCU56_RS03150	674038..674112	+	75	Protein_610	DUF3265 domain-containing protein	-
OCU56_RS03155	674567..675127	+	561	WP_261874124.1	ricin-type beta-trefoil lectin domain protein	-
OCU56_RS03160	675199..675939	-	741	WP_261874125.1	DUF1499 domain-containing protein	-
OCU56_RS03165	676199..676669	+	471	WP_261874126.1	zinc ribbon-containing protein	-
OCU56_RS03170	676739..678280	-	1542	WP_261874127.1	apolipoprotein N-acyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-85)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (12-72)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11310.24 Da
• Isoelectric Point: 10.5588

>T39809 WP_261874122.1 NZ_AP024900:c673743-673453 [Vibrio rarus]
MTYKVNFKKSALKEWQKLGYTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVITVTVLAVGK
RERSDVYRKAMKRLDD

Nucleotide

• Length: 291 bp

>T39809 NZ_AP024900:c673743-673453 [Vibrio rarus]
ATGACCTATAAAGTCAACTTTAAAAAGAGCGCACTCAAAGAGTGGCAAAAGCTTGGCTATACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCGCATGTTCCGGCTTCAAAACTTTCTGGAGCTGACAATATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGATGATGTCATCACTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCGATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9069.35 Da
• Isoelectric Point: 3.9490

>AT39809 WP_261874123.1 NZ_AP024900:c673981-673733 [Vibrio rarus]
MTSRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEDSISVNMD
DL

Nucleotide

• Length: 249 bp

>AT39809 NZ_AP024900:c673981-673733 [Vibrio rarus]
ATGACCTCTAGAATTTTAGCCGATGTAGCTGCAAGTATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACGAGTGC
TTACGGTGAACCTGTTGCTGTACTGAACCGAAATGAGCCAGCATTTTATTGCGTACCAGCCGAAGCATACGAAATGATGA
TGGATAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCAGAAGATAGCATTTCGGTAAATATGGAT
GACCTATAA