Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1200813..1201353 Replicon chromosome
Accession NZ_AP024895
Organism Vibrio porteresiae DSM 19223 strain MSSRF30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV11_RS05620 Protein ID WP_068713044.1
Coordinates 1200813..1201082 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV11_RS05625 Protein ID WP_261895555.1
Coordinates 1201075..1201353 (-) Length 93 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV11_RS05595 1196256..1196771 - 516 WP_261895549.1 RNA methyltransferase -
OCV11_RS05600 1196818..1197351 - 534 WP_261895550.1 GNAT family N-acetyltransferase -
OCV11_RS05605 1197481..1198794 + 1314 WP_261895551.1 amidohydrolase -
OCV11_RS05610 1199143..1199931 + 789 WP_261895553.1 hypothetical protein -
OCV11_RS05615 1200017..1200694 - 678 WP_225251730.1 monofunctional biosynthetic peptidoglycan transglycosylase -
OCV11_RS05620 1200813..1201082 - 270 WP_068713044.1 type II toxin-antitoxin system YafQ family toxin Toxin
OCV11_RS05625 1201075..1201353 - 279 WP_261895555.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OCV11_RS05630 1201676..1202311 + 636 WP_261895557.1 LysE family translocator -
OCV11_RS05635 1202348..1203196 - 849 WP_261895558.1 NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase -
OCV11_RS05640 1203296..1204198 + 903 WP_261895560.1 ADP-ribosylglycohydrolase family protein -
OCV11_RS05645 1204382..1204795 + 414 WP_261895561.1 DoxX family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-89)

Antitoxin

(1-85)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10332.98 Da        Isoelectric Point: 8.9074

>T39803 WP_068713044.1 NZ_AP024895:c1201082-1200813 [Vibrio porteresiae DSM 19223]
MYSLEYSTQFKKDFKKITKMPIPDIIEVGNIISKLQRGETLAPQNVDHPLTGNWVGFRDCHVKPDLVLIYRIYNQQLQLA
RIGSHSDLF

Download         Length: 270 bp

>T39803 NZ_AP024895:c1201082-1200813 [Vibrio porteresiae DSM 19223]
ATGTATAGTCTCGAGTATTCAACTCAATTTAAGAAAGACTTTAAGAAGATAACTAAAATGCCGATTCCGGATATTATTGA
GGTCGGCAATATCATATCCAAACTTCAGCGAGGGGAAACTCTTGCCCCACAAAATGTAGACCATCCACTCACAGGCAATT
GGGTGGGTTTTAGAGATTGTCACGTCAAACCCGATTTAGTGCTTATTTACCGTATTTATAATCAACAACTACAACTTGCT
CGTATCGGCTCACACAGCGATTTGTTTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10075.53 Da        Isoelectric Point: 5.1098

>AT39803 WP_261895555.1 NZ_AP024895:c1201353-1201075 [Vibrio porteresiae DSM 19223]
MRTEMLSTRIDHETKVAFTSICDEMGLSTSQAIKLFAKAVINHGGIPFELRVTQPNEITAAAIKELVEGKGHQAESLDAM
FDELTDGKVKNV

Download         Length: 279 bp

>AT39803 NZ_AP024895:c1201353-1201075 [Vibrio porteresiae DSM 19223]
ATGAGAACAGAAATGTTGAGCACTCGTATTGATCATGAAACAAAAGTGGCTTTCACTAGCATATGCGATGAGATGGGATT
AAGTACTTCGCAAGCCATTAAATTGTTTGCCAAAGCAGTCATCAATCACGGCGGTATTCCTTTCGAACTGCGCGTCACGC
AACCGAATGAAATCACAGCTGCCGCAATAAAAGAGCTAGTTGAGGGCAAGGGTCACCAAGCAGAATCGCTTGATGCCATG
TTCGATGAGTTGACTGATGGTAAGGTCAAAAATGTATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References