Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 310966..311482 Replicon chromosome
Accession NZ_AP024886
Organism Vibrio neonatus strain JCM 21521

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCU38_RS14120 Protein ID WP_261824842.1
Coordinates 311213..311482 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OCU38_RS14115 Protein ID WP_261824841.1
Coordinates 310966..311220 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU38_RS14090 306156..306629 + 474 WP_261824836.1 DUF4442 domain-containing protein -
OCU38_RS14095 306830..308326 + 1497 WP_261824837.1 alanine/glycine:cation symporter family protein -
OCU38_RS14100 308679..308984 + 306 WP_261824838.1 hypothetical protein -
OCU38_RS14105 309144..309569 + 426 WP_261824839.1 MarR family winged helix-turn-helix transcriptional regulator -
OCU38_RS14110 309808..310728 + 921 WP_261824840.1 hypothetical protein -
OCU38_RS14115 310966..311220 + 255 WP_261824841.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OCU38_RS14120 311213..311482 + 270 WP_261824842.1 Txe/YoeB family addiction module toxin Toxin
OCU38_RS14125 312026..313225 - 1200 WP_261824843.1 DUF3179 domain-containing protein -
OCU38_RS14130 313281..313712 - 432 WP_261824844.1 hypothetical protein -
OCU38_RS14135 313770..315218 - 1449 WP_261824845.1 guanitoxin biosynthesis MBL fold metallo-hydrolase GntH -
OCU38_RS14140 315372..316271 + 900 WP_261824846.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10584.97 Da        Isoelectric Point: 8.8578

>T39800 WP_261824842.1 NZ_AP024886:311213-311482 [Vibrio neonatus]
MSSSQRLLSWTDDAWGDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDDQVI
TIISCRYHY

Download         Length: 270 bp

>T39800 NZ_AP024886:311213-311482 [Vibrio neonatus]
ATGAGTAGCAGTCAACGTTTACTGTCGTGGACGGATGATGCTTGGGGTGACTACTTGTATTGGCAAACCCAAGACAAAAA
AACACTCAAGCGCATCAACAAACTCATTAACGATGTTAAGCGTTCTCCTTTCGAGGGTATTGGTAAACCTGAACCATTAA
AAGAAAATTTATCTGGTTTTTGGTCTCGTCGTATTGACGACACTAATCGACTTGTTTACGCAGTCGATGATCAAGTCATA
ACGATAATTTCGTGTCGTTATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9511.64 Da        Isoelectric Point: 4.7914

>AT39800 WP_261824841.1 NZ_AP024886:310966-311220 [Vibrio neonatus]
MRIVSFTEARNGLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNAEHLNRSIEQYRAGKATTRE
LIDE

Download         Length: 255 bp

>AT39800 NZ_AP024886:310966-311220 [Vibrio neonatus]
ATGAGAATAGTATCTTTTACTGAGGCTAGAAATGGCCTTAAAGCGGTTTTGGACGGTGTAGTTAATGATGCAGACACAAC
CGTTATTACACGCCGTGATTCTGAAGATGCTGTGGTTATGTCTTTAGATTACTACAATAGTCTTATGGAGACAGTTCACT
TACTACGCTCTCCTCAAAATGCTGAACACCTAAACCGTTCGATAGAACAGTATCGTGCAGGCAAAGCAACCACACGCGAG
TTAATTGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References