Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 9746..10635 Replicon chromosome
Accession NZ_AP024886
Organism Vibrio neonatus strain JCM 21521

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OCU38_RS12860 Protein ID WP_261824982.1
Coordinates 9746..10117 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag OCU38_RS12865 Protein ID WP_261824650.1
Coordinates 10183..10635 (-) Length 151 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU38_RS12845 5102..6649 + 1548 WP_261824648.1 glycerol-3-phosphate dehydrogenase -
OCU38_RS12850 7013..8008 + 996 WP_261824649.1 HlyD family secretion protein -
OCU38_RS12855 8041..9534 + 1494 WP_261824981.1 DHA2 family efflux MFS transporter permease subunit -
OCU38_RS12860 9746..10117 - 372 WP_261824982.1 PIN domain-containing protein Toxin
OCU38_RS12865 10183..10635 - 453 WP_261824650.1 helix-turn-helix domain-containing protein Antitoxin
OCU38_RS12870 10921..11748 + 828 WP_261824651.1 SDR family oxidoreductase -
OCU38_RS12875 11765..12730 - 966 WP_261824652.1 hypothetical protein -
OCU38_RS12880 12724..15288 - 2565 WP_261824653.1 LuxQ periplasmic sensor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-91)

Antitoxin

Helix-turn-helix domain, group 17

(80-127)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13893.81 Da        Isoelectric Point: 4.3841

>T39799 WP_261824982.1 NZ_AP024886:c10117-9746 [Vibrio neonatus]
MYLSNTGLFRARWTEQIHNEWIRNLLKNNPNADPVKIQRTKELMNAHVPDCLVEGYEALIDGLTLPDVDDRHVVAAAIKG
QAESIITFNLKDFPISELEPLGLTAIHPDEFLCDMFELDSSAC

Download         Length: 372 bp

>T39799 NZ_AP024886:c10117-9746 [Vibrio neonatus]
ATGTATCTATCTAATACTGGGTTATTTAGAGCACGATGGACAGAACAAATACATAATGAATGGATTCGAAATCTGCTCAA
GAATAACCCAAATGCAGATCCGGTAAAGATACAAAGAACTAAAGAGTTAATGAACGCACATGTTCCTGATTGTCTAGTGG
AAGGATATGAAGCGTTAATTGACGGATTAACTTTACCTGATGTCGACGATAGGCACGTTGTTGCCGCTGCTATCAAAGGG
CAAGCGGAGTCTATCATTACCTTCAATCTAAAAGACTTTCCTATAAGTGAATTGGAACCGCTAGGTTTAACTGCAATACA
CCCAGATGAGTTCCTATGTGACATGTTTGAGCTAGATAGTAGTGCTTGCTAA

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 16525.81 Da        Isoelectric Point: 4.6830

>AT39799 WP_261824650.1 NZ_AP024886:c10635-10183 [Vibrio neonatus]
MNTATKLPSAEEIALAKLGSQELSAVIEANGEAQRINVVDKSGKTHEVTIPSSALNMMIEVLTQLGQGNSVSITPIHAEL
TTQEGADMLNMSRPTFIKLLDAKQIPFSRTGNRRKVAYADLMEYKNRLEENRLTSLAELSELDQEMDMGY

Download         Length: 453 bp

>AT39799 NZ_AP024886:c10635-10183 [Vibrio neonatus]
ATGAATACTGCTACAAAATTGCCAAGCGCTGAAGAAATTGCACTGGCTAAGCTTGGTAGTCAAGAGTTGTCTGCCGTTAT
AGAAGCGAATGGTGAGGCTCAAAGAATTAATGTGGTCGACAAGTCAGGTAAGACTCATGAAGTCACCATTCCATCAAGTG
CGTTAAACATGATGATAGAAGTGCTTACTCAATTAGGGCAAGGGAACTCTGTCAGCATTACTCCTATTCATGCAGAACTT
ACAACACAAGAAGGTGCGGATATGCTAAATATGTCTAGACCTACATTCATTAAGCTTCTTGATGCAAAACAAATTCCGTT
TAGCCGCACTGGCAATCGTAGGAAGGTCGCGTACGCCGATCTTATGGAATATAAAAACCGTTTAGAAGAAAACAGACTCA
CGAGTCTTGCAGAATTATCCGAACTAGATCAAGAAATGGATATGGGATATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References