39796

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/-
Location 1490665..1491440 Replicon chromosome
Accession NZ_AP024885
Organism Vibrio neonatus strain JCM 21521

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag OCU38_RS06885 Protein ID WP_261822494.1
Coordinates 1490665..1490928 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag OCU38_RS06890 Protein ID WP_261822495.1
Coordinates 1490928..1491440 (+) Length 171 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU38_RS06855 1486035..1487771 + 1737 WP_261822489.1 DEAD/DEAH box helicase -
OCU38_RS06860 1487948..1488226 + 279 WP_021712865.1 50S ribosomal protein L25 -
OCU38_RS06865 1488407..1488658 - 252 WP_261822490.1 DUF1289 domain-containing protein -
OCU38_RS06870 1488815..1489303 + 489 WP_261822491.1 META domain-containing protein -
OCU38_RS06875 1489427..1489945 - 519 WP_261822492.1 HAD family hydrolase -
OCU38_RS06880 1489958..1490353 - 396 WP_261822493.1 DUF3465 domain-containing protein -
OCU38_RS06885 1490665..1490928 + 264 WP_261822494.1 DUF4160 domain-containing protein Toxin
OCU38_RS06890 1490928..1491440 + 513 WP_261822495.1 transcriptional regulator Antitoxin
OCU38_RS06895 1491684..1493372 + 1689 WP_261822496.1 NAD-dependent malic enzyme -
OCU38_RS06900 1493522..1494163 + 642 WP_261824249.1 ElyC/SanA/YdcF family protein -
OCU38_RS06905 1494334..1495290 + 957 WP_261822497.1 thioredoxin-disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(10-75)

Antitoxin

Uncharacterized protein HI1420

(84-165)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9836.48 Da        Isoelectric Point: 9.4837

>T39796 WP_261822494.1 NZ_AP024885:1490665-1490928 [Vibrio neonatus]
VPEILRKLLGLRFAMYLLDDGAHNRPHIHVRYGEHQASIAIDDIELLAGYLPPKKLKTAEKYILEHQAALLIAWNGAIQG
TSIRRVN

Download         Length: 264 bp

>T39796 NZ_AP024885:1490665-1490928 [Vibrio neonatus]
GTGCCTGAGATACTAAGGAAACTGCTAGGGTTACGCTTTGCAATGTATCTATTGGATGATGGGGCTCATAATCGACCACA
CATTCACGTTAGGTATGGCGAACATCAAGCTTCTATCGCTATCGATGATATAGAGCTACTTGCAGGCTATCTTCCTCCTA
AAAAATTAAAAACAGCTGAGAAGTACATTCTAGAGCACCAAGCTGCATTATTGATCGCATGGAATGGCGCAATACAAGGT
ACATCTATTCGGAGAGTAAACTAA

Antitoxin


Download         Length: 171 a.a.        Molecular weight: 18979.33 Da        Isoelectric Point: 5.0428

>AT39796 WP_261822495.1 NZ_AP024885:1490928-1491440 [Vibrio neonatus]
MLKIIDVDWENGFELELEFSDGFKGKADLTEIFQSAAFAHVESFTEFSLEGSHLDWGNAEISANKLRQLAQNNGDYLPAK
QRTISANDMEAVIKQAAWDSITLNRPDILQAAIRGYIEEYGVQKVQAKTNLKSRPSIYKALSPRTSPKFDTLVQLAHGAF
AVKADTEAQR

Download         Length: 513 bp

>AT39796 NZ_AP024885:1490928-1491440 [Vibrio neonatus]
ATGCTAAAGATCATTGATGTTGATTGGGAAAACGGCTTTGAACTGGAGCTAGAGTTTAGCGATGGCTTTAAAGGCAAAGC
AGATCTTACTGAAATCTTCCAATCTGCAGCATTTGCTCACGTCGAGTCTTTCACTGAATTTTCCTTGGAAGGTTCACACC
TTGACTGGGGTAATGCTGAAATATCCGCAAACAAGTTACGACAGCTTGCGCAAAATAATGGTGATTACCTACCCGCAAAA
CAGCGAACGATTTCAGCCAACGACATGGAAGCGGTCATCAAGCAAGCCGCTTGGGATTCAATCACCCTAAATCGCCCAGA
CATATTACAAGCGGCTATTCGAGGTTATATCGAAGAATATGGGGTGCAAAAAGTTCAAGCCAAAACCAACCTTAAAAGCA
GACCGAGTATCTATAAGGCTCTAAGCCCAAGAACCTCGCCAAAATTTGATACCTTAGTCCAATTGGCTCATGGCGCATTC
GCTGTAAAAGCCGACACGGAAGCACAACGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References