Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 956863..957665 Replicon chromosome
Accession NZ_AP024885
Organism Vibrio neonatus strain JCM 21521

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU38_RS04460 Protein ID WP_261823907.1
Coordinates 957129..957665 (+) Length 179 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU38_RS04455 Protein ID WP_261823906.1
Coordinates 956863..957132 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU38_RS04440 952522..954453 + 1932 WP_261823904.1 DUF262 domain-containing HNH endonuclease family protein -
OCU38_RS04445 954903..956468 + 1566 WP_152821910.1 polysaccharide lyase 6 family protein -
OCU38_RS04450 956527..956730 + 204 WP_261823905.1 hypothetical protein -
OCU38_RS04455 956863..957132 + 270 WP_261823906.1 DUF1778 domain-containing protein Antitoxin
OCU38_RS04460 957129..957665 + 537 WP_261823907.1 GNAT family N-acetyltransferase Toxin
OCU38_RS04465 957800..958648 + 849 WP_261823908.1 LysR family transcriptional regulator -
OCU38_RS04470 958757..959482 + 726 WP_261823909.1 hypothetical protein -
OCU38_RS04475 959542..959973 + 432 WP_261823910.1 glycine zipper family protein -
OCU38_RS04480 960090..960329 + 240 WP_261823911.1 hypothetical protein -
OCU38_RS04485 960613..962232 + 1620 WP_261823912.1 guanitoxin biosynthesis MBL fold metallo-hydrolase GntH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(3-81)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 20300.57 Da        Isoelectric Point: 9.6696

>T39794 WP_261823907.1 NZ_AP024885:957129-957665 [Vibrio neonatus]
VSWGNEFVELNKSKHDRTSFDCGERELNTFIRTQAVKHMQAGISRTMVLPCSQPLLNQKYAICAFYTVAPSSISRETLPA
QHAKKLPRYPIPVFLLAQLGVHKEFHGSGLDKVSLIRALKYLWQVNHHMRAYAIVVDCLTDSAQAFYTKFGFQVLCEHNG
RVRMFLPMNTVVQLFNQG

Download         Length: 537 bp

>T39794 NZ_AP024885:957129-957665 [Vibrio neonatus]
GTGAGTTGGGGTAATGAGTTCGTAGAACTTAATAAATCCAAGCATGATCGCACTTCATTTGATTGCGGTGAGCGAGAACT
AAATACATTTATCAGGACTCAAGCAGTAAAACACATGCAAGCAGGTATTAGCCGAACTATGGTTCTACCTTGCTCTCAAC
CACTGCTAAATCAGAAATATGCAATTTGTGCTTTTTACACTGTAGCACCTAGTTCTATTAGCCGAGAAACATTGCCAGCG
CAACATGCCAAGAAACTGCCTCGATATCCCATTCCTGTTTTTCTTTTGGCTCAGCTAGGAGTGCATAAAGAGTTTCATGG
CTCTGGGTTAGATAAAGTCAGTCTAATCCGTGCTCTAAAGTATCTATGGCAAGTTAACCACCATATGCGGGCATACGCCA
TTGTCGTGGATTGCCTTACTGACTCAGCGCAAGCGTTCTATACCAAGTTTGGTTTTCAAGTGTTGTGTGAACATAATGGA
CGTGTTCGTATGTTCCTGCCAATGAACACAGTCGTACAGCTTTTTAACCAAGGGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9872.19 Da        Isoelectric Point: 4.3324

>AT39794 WP_261823906.1 NZ_AP024885:956863-957132 [Vibrio neonatus]
MASARLDIRLDEEIKARAEKASALLGLKSLTEYVVRLMDEDATQVIEQHESIVVKDSVFDEFMAACDKANTPNQALLEAA
RFTDESGIK

Download         Length: 270 bp

>AT39794 NZ_AP024885:956863-957132 [Vibrio neonatus]
ATGGCATCTGCACGTTTAGATATTCGTCTTGATGAAGAGATCAAGGCTAGAGCTGAAAAAGCATCCGCGTTACTTGGTCT
AAAAAGTTTAACTGAATATGTTGTTAGGCTTATGGATGAAGATGCTACTCAGGTAATTGAGCAGCATGAAAGTATCGTAG
TTAAGGATAGTGTGTTTGACGAATTTATGGCTGCTTGCGATAAGGCCAATACGCCAAATCAGGCGTTGCTTGAAGCGGCT
AGGTTCACTGATGAGAGCGGCATTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References