Detailed information of TA system TA039792

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 3534917..3535457
• Replicon: chromosome
• Accession: NZ_AP024883
• Organism: Vibrio mangrovi strain CECT 7927

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCU74_RS15775
• Protein ID: WP_087481966.1
• Coordinates: 3534917..3535186 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU74_RS15780
• Protein ID: WP_087482053.1
• Coordinates: 3535179..3535457 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU74_RS15750	3530096..3530974	-	879	WP_200807761.1	LysR substrate-binding domain-containing protein	-
OCU74_RS15755	3531121..3532329	+	1209	WP_087481962.1	tetratricopeptide repeat protein	-
OCU74_RS15760	3532332..3533330	+	999	WP_087481963.1	DMT family transporter	-
OCU74_RS15765	3533646..3534434	+	789	WP_087481964.1	class D beta-lactamase	-
OCU74_RS15770	3534415..3534891	+	477	WP_087481965.1	GNAT family N-acetyltransferase	-
OCU74_RS15775	3534917..3535186	-	270	WP_087481966.1	type II toxin-antitoxin system YafQ family toxin	Toxin
OCU74_RS15780	3535179..3535457	-	279	WP_087482053.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (3-83)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10193.75 Da
• Isoelectric Point: 6.8674

>T39792 WP_087481966.1 NZ_AP024883:c3535186-3534917 [Vibrio mangrovi]
MYSLEYSTQFKKDFKTMTKMPIPDIIEIGNIISQLQRGETLAPHNVDHALTGSWAGFRDCHIKPDLVLIYRIFDGQLQLA
RIGSHSDLF

Nucleotide

• Length: 270 bp

>T39792 NZ_AP024883:c3535186-3534917 [Vibrio mangrovi]
ATGTATAGCCTTGAATACTCAACCCAGTTTAAAAAAGACTTTAAGACAATGACCAAAATGCCGATCCCAGACATCATTGA
GATCGGCAATATTATTTCACAATTGCAAAGAGGTGAAACTCTTGCACCTCACAACGTTGACCACGCACTCACTGGGAGTT
GGGCCGGTTTTCGTGACTGCCATATAAAACCAGATTTAGTACTTATTTACCGCATTTTTGATGGGCAATTACAACTTGCA
CGAATTGGTTCCCACAGCGATTTGTTTTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 9930.39 Da
• Isoelectric Point: 6.2192

>AT39792 WP_087482053.1 NZ_AP024883:c3535457-3535179 [Vibrio mangrovi]
MRTEMLSTRIDHDTKAAFTSICDEMGLSTSQAIKLFAKAVINHGGIPFELRVAQPNEVTAAAMKELVEGKGHKAESVDAM
LNDLTEGKAKNV

Nucleotide

• Length: 279 bp

>AT39792 NZ_AP024883:c3535457-3535179 [Vibrio mangrovi]
ATGAGAACAGAAATGTTGAGCACCCGCATAGACCATGACACCAAAGCTGCGTTTACCAGCATTTGTGATGAAATGGGTTT
AAGCACCTCACAAGCTATTAAATTGTTTGCCAAAGCAGTCATCAACCACGGTGGTATTCCTTTCGAACTCCGTGTGGCAC
AGCCTAACGAGGTCACTGCTGCAGCTATGAAAGAGCTGGTCGAAGGTAAAGGTCATAAAGCCGAGTCCGTTGATGCGATG
CTCAACGACCTGACCGAAGGCAAAGCAAAAAATGTATAG