Detailed information of TA system TA039791

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 3190003..3190550
• Replicon: chromosome
• Accession: NZ_AP024883
• Organism: Vibrio mangrovi strain CECT 7927

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCU74_RS14125
• Protein ID: WP_087482345.1
• Coordinates: 3190003..3190305 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU74_RS14130
• Protein ID: WP_087482344.1
• Coordinates: 3190293..3190550 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU74_RS14090	3185853..3186383	+	531	WP_087482350.1	inorganic diphosphatase	-
OCU74_RS14095	3186638..3187054	-	417	WP_087482349.1	GFA family protein	-
OCU74_RS14100	3187170..3187340	+	171	Protein_2721	IS110 family transposase	-
OCU74_RS14105	3187363..3188010	-	648	WP_087482348.1	hypothetical protein	-
OCU74_RS14110	3188119..3188247	+	129	Protein_2723	IS110 family transposase	-
OCU74_RS14115	3188363..3188833	-	471	WP_087482347.1	ABZJ_00895 family protein	-
OCU74_RS14120	3189284..3189823	-	540	WP_143693289.1	hypothetical protein	-
OCU74_RS14125	3190003..3190305	-	303	WP_087482345.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCU74_RS14130	3190293..3190550	-	258	WP_087482344.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCU74_RS14135	3190848..3191012	+	165	WP_159457464.1	hypothetical protein	-
OCU74_RS14140	3191243..3191587	+	345	WP_087482343.1	DUF4258 domain-containing protein	-
OCU74_RS14145	3191615..3192058	+	444	WP_087482342.1	hypothetical protein	-
OCU74_RS14150	3192238..3193200	+	963	WP_087482341.1	HEPN domain-containing protein	-
OCU74_RS14155	3193291..3194124	-	834	WP_087482340.1	hypothetical protein	-
OCU74_RS14160	3194207..3194758	-	552	WP_087482339.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3187363..3196559	9196
	-	flank	IS/Tn	-	-	3188119..3188289	170

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11707.56 Da
• Isoelectric Point: 4.8951

>T39791 WP_087482345.1 NZ_AP024883:c3190305-3190003 [Vibrio mangrovi]
MAEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLEAFPESGRIPPEIEHLSYREIVVGPCRIFYKQDNDRV
YILFVLRAERDLRKFLLNKQ

Nucleotide

• Length: 303 bp

>T39791 NZ_AP024883:c3190305-3190003 [Vibrio mangrovi]
ATGGCTGAAATAATCTGGACTGAACCCGCGTTATCCGACCTCAATGATATTGCTGAATACATAGCGCTTGAAAACGTAGT
CGCTGCAAAGCAATTGGTTCAGACTGTCTTCACTAAAGTTGAGCGCTTAGAAGCTTTTCCAGAGTCAGGTCGTATTCCAC
CTGAAATTGAACATCTTAGTTACCGTGAGATCGTTGTCGGTCCTTGCCGTATTTTCTACAAACAAGATAATGACAGAGTC
TATATTTTGTTTGTTCTGCGTGCAGAAAGAGATTTACGAAAGTTCCTGTTGAATAAGCAGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9717.29 Da
• Isoelectric Point: 7.3182

>AT39791 WP_087482344.1 NZ_AP024883:c3190550-3190293 [Vibrio mangrovi]
MKVELVTSLKRQATKILADLRDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLVILEGIARGERALADGKVVHHEEAKDKM
SKWLK

Nucleotide

• Length: 258 bp

>AT39791 NZ_AP024883:c3190550-3190293 [Vibrio mangrovi]
ATGAAAGTAGAACTAGTTACATCACTTAAACGTCAGGCAACGAAGATCCTTGCTGATCTGCGCGACACTAAAGAACCCGT
GTTGATTACCGAGCATGGTAAACCATCGGCATATCTGGTCGATGTTGATGATTATGAGTTTATGCAAAACCGCTTGGTCA
TTCTTGAAGGGATTGCCCGAGGAGAGCGTGCTTTAGCTGACGGTAAAGTTGTTCATCATGAGGAAGCTAAGGACAAAATG
TCAAAATGGCTGAAATAA