Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1770476..1771035 Replicon chromosome
Accession NZ_AP024881
Organism Vibrio ishigakensis strain C1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Pcarn_RS08000 Protein ID WP_261833341.1
Coordinates 1770757..1771035 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Pcarn_RS07995 Protein ID WP_261833340.1
Coordinates 1770476..1770757 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pcarn_RS07965 1765512..1765952 + 441 WP_261833335.1 DUF411 domain-containing protein -
Pcarn_RS07970 1766500..1767771 + 1272 WP_261833336.1 divalent metal cation transporter -
Pcarn_RS07975 1767909..1768877 + 969 WP_261833337.1 AEC family transporter -
Pcarn_RS07980 1768981..1769676 + 696 WP_261833338.1 amino acid racemase -
Pcarn_RS07985 1769742..1770083 + 342 WP_261835659.1 DUF202 domain-containing protein -
Pcarn_RS07990 1770080..1770406 + 327 WP_261833339.1 DUF202 domain-containing protein -
Pcarn_RS07995 1770476..1770757 + 282 WP_261833340.1 DUF1778 domain-containing protein Antitoxin
Pcarn_RS08000 1770757..1771035 + 279 WP_261833341.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Pcarn_RS08005 1771409..1773313 - 1905 WP_261833342.1 TRAP transporter fused permease subunit -
Pcarn_RS08010 1773392..1774318 - 927 WP_261833343.1 TAXI family TRAP transporter solute-binding subunit -
Pcarn_RS08015 1774501..1775418 - 918 WP_261833344.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-79)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11182.85 Da        Isoelectric Point: 4.9001

>T39789 WP_261833341.1 NZ_AP024881:1770757-1771035 [Vibrio ishigakensis]
MIFWEEKSLDDREKIFEFLYDFNPIAAERTDELIEQNVEQLKSHPEMGVQRDSIRGRLLIIPEISMIVSYWKDDTNIRVM
RVLHQKQKFPWT

Download         Length: 279 bp

>T39789 NZ_AP024881:1770757-1771035 [Vibrio ishigakensis]
ATGATTTTCTGGGAAGAAAAGTCGCTTGATGATAGAGAAAAGATCTTCGAGTTTCTTTACGACTTTAATCCAATAGCAGC
AGAACGAACCGACGAACTCATTGAGCAGAATGTAGAACAGTTAAAGTCACACCCAGAAATGGGTGTACAACGTGATAGTA
TCCGCGGTCGGCTGTTAATCATCCCAGAGATATCCATGATCGTCTCTTACTGGAAAGATGATACCAACATCCGAGTGATG
CGTGTTCTGCATCAAAAGCAGAAATTCCCTTGGACATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10913.06 Da        Isoelectric Point: 6.4751

>AT39789 WP_261833340.1 NZ_AP024881:1770476-1770757 [Vibrio ishigakensis]
MDTRIQFRVDEETKRLAQQRAESQGRTLSDACRELTESLAEEQRQAMSQETWLTEQVNEAFAKYDEGKAVFHNHDSAKSL
IEQRKAKIRNRDK

Download         Length: 282 bp

>AT39789 NZ_AP024881:1770476-1770757 [Vibrio ishigakensis]
ATGGATACCAGAATTCAATTCAGAGTCGATGAAGAGACCAAACGTCTGGCTCAGCAAAGAGCGGAAAGCCAAGGTCGAAC
CTTAAGCGATGCATGTCGAGAACTCACTGAATCATTGGCAGAAGAACAGCGCCAAGCGATGTCACAAGAAACTTGGTTGA
CCGAGCAGGTGAATGAAGCCTTTGCCAAATATGACGAAGGTAAGGCCGTATTCCATAACCACGACTCAGCTAAAAGCCTT
ATTGAACAACGCAAGGCTAAGATTCGAAACCGAGACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References