Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 124211..124759 Replicon chromosome
Accession NZ_AP024865
Organism Vibrio breoganii strain CAIM 1829

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCU35_RS13830 Protein ID WP_261826294.1
Coordinates 124211..124510 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OCU35_RS13835 Protein ID WP_102427610.1
Coordinates 124517..124759 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU35_RS13810 120396..121325 - 930 WP_102360358.1 NADP-dependent oxidoreductase -
OCU35_RS13815 121398..121820 - 423 WP_017028230.1 organic hydroperoxide resistance protein -
OCU35_RS13820 121944..122387 + 444 WP_102334549.1 MarR family transcriptional regulator -
OCU35_RS13825 122846..124138 + 1293 WP_102443538.1 DEAD/DEAH box helicase -
OCU35_RS13830 124211..124510 - 300 WP_261826294.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU35_RS13835 124517..124759 - 243 WP_102427610.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU35_RS13840 125017..125706 + 690 WP_261826295.1 zinc metallopeptidase -
OCU35_RS13845 126068..126427 + 360 WP_261826296.1 carboxymuconolactone decarboxylase family protein -
OCU35_RS13850 126427..126942 + 516 WP_102427612.1 VOC family protein -
OCU35_RS13855 126939..127382 + 444 WP_261826297.1 DMT family transporter -
OCU35_RS13860 127379..127885 + 507 WP_261826298.1 DMT family transporter -
OCU35_RS13865 127875..128198 + 324 WP_261826299.1 hypothetical protein -
OCU35_RS13870 128288..129226 + 939 WP_261826300.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11328.91 Da        Isoelectric Point: 9.3901

>T39780 WP_261826294.1 NZ_AP024865:c124510-124211 [Vibrio breoganii]
MPKSNCKLSRLAQSHLQKIKSYTVNNFSEAQWRNYKEVLLTGFQMLADNPAVGRNCDDIYANGYYFPVGKHTAYFTKEDG
FILVVAVLSQSQLPQNHLR

Download         Length: 300 bp

>T39780 NZ_AP024865:c124510-124211 [Vibrio breoganii]
ATGCCAAAGAGCAATTGCAAACTAAGCAGATTAGCACAGTCTCATTTGCAGAAAATCAAAAGCTATACTGTTAACAATTT
TTCAGAAGCACAATGGCGAAATTATAAGGAAGTACTGCTTACCGGATTCCAGATGCTCGCTGATAACCCTGCTGTCGGTA
GAAACTGTGACGATATCTACGCAAACGGATACTACTTCCCTGTTGGCAAACACACAGCATATTTTACCAAAGAAGATGGT
TTCATTTTGGTAGTGGCTGTACTCAGTCAATCACAGTTGCCGCAAAACCATCTAAGATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9090.33 Da        Isoelectric Point: 5.1006

>AT39780 WP_102427610.1 NZ_AP024865:c124759-124517 [Vibrio breoganii]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKVDYLRHCFESAKQDLAQGNVIDGEDFFRAL

Download         Length: 243 bp

>AT39780 NZ_AP024865:c124759-124517 [Vibrio breoganii]
ATGCACACATTGACAGCAAATGATGCGAAACGTAATTTTGGCGAGTTACTTCTTAGTGCTCAACGTGAACCTGTCAAGAT
TAGCAAAAACAGCAAAGACGCTGTAGTTGTTATGTCTATTAAAGATTATGAAGAGCTAGAAGCCATGAAGGTTGATTACC
TCAGGCATTGCTTTGAGTCTGCAAAGCAAGATTTAGCTCAAGGAAATGTCATTGATGGTGAAGATTTTTTTAGAGCTTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References