Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 39616..40391 Replicon chromosome
Accession NZ_AP024855
Organism Photobacterium toruni strain CECT 9189

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OC457_RS14350 Protein ID WP_210436072.1
Coordinates 39616..40122 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1T4QYG4
Locus tag OC457_RS14355 Protein ID WP_017018730.1
Coordinates 40119..40391 (-) Length 91 a.a.

Genomic Context

OC457_RS14335OC457_RS14345OC457_RS14360OC457_RS14365OC457_RS14325OC457_RS14330OC457_RS14340OC457_RS14350OC457_RS14355OC457_RS14370OC457_RS14375OC457_RS14380OC457_RS14385
Location: 37300..38436 (1137 bp)
Type: Others
Protein ID: WP_096777823.1
Location: 39008..39490 (483 bp)
Type: Others
Protein ID: WP_080174020.1
Location: 40696..41151 (456 bp)
Type: Others
Protein ID: WP_012535201.1
Location: 41144..41311 (168 bp)
Type: Others
Protein ID: WP_235866910.1
Location: 34942..35709 (768 bp)
Type: Others
Protein ID: WP_080174018.1
Location: 35699..36541 (843 bp)
Type: Others
Protein ID: WP_080174019.1
Location: 38485..38724 (240 bp)
Type: Others
Protein ID: Protein_43
Location: 39616..40122 (507 bp)
Type: Toxin
Protein ID: WP_210436072.1
Location: 40119..40391 (273 bp)
Type: Antitoxin
Protein ID: WP_017018730.1
Location: 41367..42212 (846 bp)
Type: Others
Protein ID: WP_080174022.1
Location: 42335..43186 (852 bp)
Type: Others
Protein ID: WP_080174023.1
Location: 43334..44614 (1281 bp)
Type: Others
Protein ID: WP_080174024.1
Location: 44993..45319 (327 bp)
Type: Others
Protein ID: WP_080174025.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OC457_RS1432534942..35709-768WP_080174018.1ABC transporter ATP-binding protein-
OC457_RS1433035699..36541-843WP_080174019.1bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase-
OC457_RS1433537300..38436+1137WP_096777823.1ATP-binding protein-
OC457_RS1434038485..38724-240Protein_43phage integrase N-terminal SAM-like domain-containing protein-
OC457_RS1434539008..39490+483WP_080174020.1lecithin retinol acyltransferase family protein-
OC457_RS1435039616..40122-507WP_210436072.1GNAT family N-acetyltransferaseToxin
OC457_RS1435540119..40391-273WP_017018730.1DUF1778 domain-containing proteinAntitoxin
OC457_RS1436040696..41151+456WP_012535201.1DUF2559 family protein-
OC457_RS1436541144..41311+168WP_235866910.1hypothetical protein-
OC457_RS1437041367..42212-846WP_080174022.1ModD protein-
OC457_RS1437542335..43186-852WP_080174023.1hypothetical protein-
OC457_RS1438043334..44614-1281WP_080174024.1dicarboxylate/amino acid:cation symporter-
OC457_RS1438544993..45319-327WP_080174025.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--38440..38727287
-insideIntegron--38440..411512711


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(84-152)

Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 19021.06 Da        Isoelectric Point: 8.9100

>T39769 WP_210436072.1 NZ_AP024855:c40122-39616 [Photobacterium toruni]
IMNTVQLEKAKHDRNRFDCGITALNNYLKVMASQQAKKDNTRTFVLEDNQCPEHIIGYYTLTMTPIDIQDLPPKLQKKHH
TVTSGGLIARLAVDHRYKGLGFGEWLLIDALRKLLMASETIAFPVVIVDAKDGAEYFYKKYGFTAFKDANNKLFITIADI
RASIGELI

Download         Length: 507 bp

>T39769 NZ_AP024855:c40122-39616 [Photobacterium toruni]
ATAATGAATACTGTCCAATTAGAAAAAGCTAAACATGACCGAAATCGTTTTGATTGTGGCATTACCGCACTCAATAATTA
CTTAAAAGTTATGGCAAGCCAACAAGCTAAGAAAGACAATACTCGTACTTTTGTTCTTGAAGATAACCAATGTCCTGAGC
ACATTATTGGTTATTACACATTAACCATGACACCCATTGATATTCAGGATTTACCTCCTAAATTACAGAAGAAACATCAC
ACTGTAACTTCGGGTGGTTTGATTGCCCGCTTAGCCGTTGACCATAGATACAAAGGTCTGGGTTTCGGTGAGTGGCTTTT
GATTGATGCGCTTAGAAAACTATTAATGGCAAGTGAAACAATCGCCTTCCCTGTCGTCATTGTTGATGCAAAAGATGGCG
CTGAATATTTCTATAAAAAATACGGCTTTACCGCATTCAAAGACGCTAATAACAAACTGTTTATTACAATTGCAGACATT
AGAGCTAGTATCGGTGAATTAATTTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9782.32 Da        Isoelectric Point: 9.8652

>AT39769 WP_017018730.1 NZ_AP024855:c40391-40119 [Photobacterium toruni]
MATALPRITARVDIDTQELLSQAAAIAGMSSINSFVLSAAVEKAKTIMERERALQLSQQDAMTLMTALDQPAKPNSKLQK
AASRYMDKTQ

Download         Length: 273 bp

>AT39769 NZ_AP024855:c40391-40119 [Photobacterium toruni]
ATGGCAACTGCATTACCTCGTATTACAGCGCGTGTAGATATTGATACACAAGAACTACTGTCTCAAGCTGCAGCTATTGC
TGGTATGTCTAGCATTAACTCATTTGTGCTTAGTGCGGCTGTAGAAAAAGCTAAAACTATTATGGAACGTGAACGTGCTC
TACAACTAAGTCAGCAAGATGCTATGACGTTAATGACAGCGTTAGACCAACCAGCTAAACCAAATAGCAAATTACAAAAA
GCCGCTTCACGCTATATGGATAAAACTCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1T4QYG4

References