Detailed information of TA system TA039767

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 2690114..2691471
• Replicon: chromosome
• Accession: NZ_AP024850
• Organism: Photobacterium sanguinicancri strain CECT 7579

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: OCU87_RS12470
• Protein ID: WP_261858384.1
• Coordinates: 2690114..2690932 (-)
• Length: 273 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: OCU87_RS12475
• Protein ID: WP_261857294.1
• Coordinates: 2691067..2691471 (-)
• Length: 135 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU87_RS12450	2686383..2687486	-	1104	WP_261857290.1	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	-
OCU87_RS12455	2687621..2688787	-	1167	WP_261857291.1	nucleotide sugar dehydrogenase	-
OCU87_RS12460	2689346..2689564	-	219	WP_261857292.1	hypothetical protein	-
OCU87_RS12465	2689591..2689866	-	276	WP_261857293.1	helix-turn-helix transcriptional regulator	-
OCU87_RS12470	2690114..2690932	-	819	WP_261858384.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
OCU87_RS12475	2691067..2691471	-	405	WP_261857294.1	DUF6088 family protein	Antitoxin
OCU87_RS12480	2691662..2691807	-	146	Protein_2362	integrase	-
OCU87_RS12485	2692083..2693645	+	1563	WP_261857295.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (1-259)

Antitoxin

• Protein of unknown function DUF6088 (9-129)

Sequences

Toxin

Protein

• Length: 273 a.a.
• Molecular weight: 31586.62 Da
• Isoelectric Point: 5.5183

>T39767 WP_261858384.1 NZ_AP024850:c2690932-2690114 [Photobacterium sanguinicancri]
MVFSGGTALAKSNVKILRMSEDVDIKLIPKPAFDELSRAKKKVARKICINEIELAITQSELFRVEARIVRDEYRYVELEL
RYPQQFNQAPCLRPIIKLELMETIPLLDVEPRSIQSLVAELYKQPQEVKAFDCVSIHATLVEKVISMLRRTMSVKRDTQR
KDDATLVRHIYDIYCILKTEEQTENYDLKALTPIFKTVLEEDIERFGNQHAEFVAAPKQELQLGLQELEENPIFRQRFQD
FVTPMVFNAEPHDFDTCFASFKSIAESLIKTI

Nucleotide

• Length: 819 bp

>T39767 NZ_AP024850:c2690932-2690114 [Photobacterium sanguinicancri]
ATGGTCTTTTCTGGTGGTACTGCGCTAGCAAAGTCAAACGTTAAAATTCTTAGAATGTCAGAAGATGTAGACATTAAATT
GATCCCTAAACCCGCATTTGATGAACTAAGTCGCGCCAAAAAGAAAGTGGCTCGTAAAATATGCATTAACGAGATTGAAC
TGGCGATCACTCAGTCAGAGCTATTCAGGGTTGAAGCGCGTATTGTTCGTGATGAGTATCGCTATGTTGAATTAGAACTC
AGATACCCGCAGCAGTTTAACCAAGCGCCCTGCCTTCGCCCCATTATTAAGCTGGAATTGATGGAGACAATCCCGTTACT
TGATGTAGAACCTCGTAGCATTCAATCACTGGTTGCGGAGCTGTATAAACAACCACAAGAAGTGAAAGCTTTCGATTGCG
TCTCGATCCACGCTACCTTAGTTGAAAAAGTGATTTCAATGTTGCGCCGTACAATGTCAGTGAAGCGCGATACACAGCGT
AAGGATGATGCCACTCTTGTGCGCCATATCTATGATATTTACTGCATTTTAAAGACTGAGGAACAGACGGAAAACTACGA
CCTTAAAGCGCTTACACCGATATTTAAAACGGTGCTTGAAGAAGACATTGAACGTTTTGGTAATCAGCATGCAGAGTTTG
TTGCCGCTCCAAAGCAAGAGCTGCAACTCGGATTGCAAGAACTTGAGGAAAACCCTATTTTTCGCCAACGCTTTCAAGAC
TTTGTCACACCAATGGTATTTAACGCCGAGCCTCATGATTTTGATACCTGCTTTGCTTCATTTAAAAGCATTGCAGAGTC
GTTAATTAAAACAATTTAA

Antitoxin

Protein

• Length: 135 a.a.
• Molecular weight: 15183.40 Da
• Isoelectric Point: 10.4087

>AT39767 WP_261857294.1 NZ_AP024850:c2691471-2691067 [Photobacterium sanguinicancri]
MTAVDRVYQKIKRSRRYVFERKDFDGFASYDQIGRVLRQLVKQGELIKLGYGLYTKARINSLTGSPMPTNPGGSDALMRE
ILKMKGVDFEMDNLSLQSLSGESTQIPSSVQYSWDPKQFNRKLAVGNRVLNSPS

Nucleotide

• Length: 405 bp

>AT39767 NZ_AP024850:c2691471-2691067 [Photobacterium sanguinicancri]
ATGACAGCTGTTGATCGTGTTTATCAAAAGATAAAGCGTTCGAGACGCTATGTTTTTGAGCGCAAAGACTTTGATGGCTT
TGCTAGCTACGACCAAATTGGTCGAGTGCTAAGGCAATTGGTTAAACAAGGTGAGTTAATAAAGCTTGGCTATGGTCTCT
ACACCAAGGCAAGGATTAACAGCCTAACAGGCAGCCCCATGCCCACTAATCCAGGGGGAAGCGATGCCCTGATGCGTGAG
ATATTAAAGATGAAAGGCGTCGATTTTGAAATGGACAACCTATCTTTACAAAGCCTATCAGGTGAAAGCACTCAAATCCC
ATCATCCGTTCAATACTCATGGGATCCTAAACAATTTAATCGCAAATTGGCTGTAGGTAACCGAGTGTTAAACTCGCCGA
GTTAA