Detailed information of TA system TA039766

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 1670380..1670945
• Replicon: chromosome
• Accession: NZ_AP024850
• Organism: Photobacterium sanguinicancri strain CECT 7579

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCU87_RS07950
• Protein ID: WP_261858207.1
• Coordinates: 1670658..1670945 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU87_RS07945
• Protein ID: WP_094958601.1
• Coordinates: 1670380..1670661 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU87_RS07915	1665931..1666257	+	327	WP_261858202.1	barstar family protein	-
OCU87_RS07920	1666326..1666712	+	387	WP_261858203.1	energy transducer TonB	-
OCU87_RS07925	1667198..1668101	-	904	Protein_1472	transposase	-
OCU87_RS07930	1668440..1668844	+	405	WP_261858204.1	hypothetical protein	-
OCU87_RS07935	1668823..1669308	+	486	WP_261858205.1	hypothetical protein	-
OCU87_RS07940	1669472..1669747	+	276	WP_261858206.1	hypothetical protein	-
OCU87_RS07945	1670380..1670661	+	282	WP_094958601.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCU87_RS07950	1670658..1670945	+	288	WP_261858207.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCU87_RS07955	1671239..1672287	+	1049	Protein_1478	tryptophan--tRNA ligase	-
OCU87_RS07960	1672759..1673145	+	387	WP_261858208.1	VOC family protein	-
OCU87_RS07965	1673321..1673584	+	264	WP_062692840.1	hypothetical protein	-
OCU87_RS07970	1673909..1674469	+	561	WP_261858209.1	hypothetical protein	-
OCU87_RS07975	1674795..1675508	+	714	WP_261858210.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1626947..1679841	52894

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10801.44 Da
• Isoelectric Point: 4.7063

>T39766 WP_261858207.1 NZ_AP024850:1670658-1670945 [Photobacterium sanguinicancri]
MNVVWSPLALDKIGQTAEYIALDNPSAAEKWVNEVFDKAENLGSFPELGRLVPELNRANYREIIFGNYRIIYSVTLRINI
LTVRNCSQLLTMADI

Nucleotide

• Length: 288 bp

>T39766 NZ_AP024850:1670658-1670945 [Photobacterium sanguinicancri]
ATGAATGTTGTTTGGTCGCCGCTTGCTTTAGACAAAATAGGGCAGACAGCAGAATACATTGCATTAGATAATCCATCTGC
GGCAGAAAAATGGGTTAATGAAGTATTCGACAAAGCAGAGAATTTAGGTTCATTTCCAGAGTTAGGTCGCCTTGTTCCTG
AGCTAAACAGAGCTAATTATCGTGAAATTATTTTTGGTAATTACCGCATTATTTATAGCGTAACGTTAAGAATAAATATT
TTAACGGTTCGTAACTGTAGTCAATTGCTGACTATGGCTGATATATAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10469.97 Da
• Isoelectric Point: 5.1745

>AT39766 WP_094958601.1 NZ_AP024850:1670380-1670661 [Photobacterium sanguinicancri]
MTRLRLDQDIQPLSEFRAGVASFIRQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEELQQAEAQIASGFGLSN
EDARSKILGRLRS

Nucleotide

• Length: 282 bp

>AT39766 NZ_AP024850:1670380-1670661 [Photobacterium sanguinicancri]
ATGACTCGACTAAGATTAGATCAAGATATTCAACCACTTTCAGAGTTTAGAGCTGGCGTAGCTTCGTTTATTCGTCAAAT
TAACGAAACTCGTAGACCTTTAGTAATTACTCAGCGTGGCAAAGGTGTCGCTGTTGTTTTAGATGTTGCTGAATATGAAG
CAATGCAAGAAAAAATAGAGTTACTGGAAGAATTGCAGCAAGCTGAAGCTCAAATCGCTAGTGGCTTCGGTTTATCAAAT
GAAGATGCTCGTTCTAAAATCTTGGGACGTTTACGTTCATGA