Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yoeB-relB/YoeB-RelB |
Location | 112872..113385 | Replicon | chromosome |
Accession | NZ_AP024802 | ||
Organism | Acinetobacter baumannii strain OCU Ac18 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A2L2M0A2 |
Locus tag | OCUAc18_RS00540 | Protein ID | WP_000203952.1 |
Coordinates | 112872..113135 (-) | Length | 88 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | S7WSW9 |
Locus tag | OCUAc18_RS00545 | Protein ID | WP_000557943.1 |
Coordinates | 113122..113385 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OCUAc18_RS00510 (OCUAc18_00950) | 108962..110392 | + | 1431 | WP_000178999.1 | amino acid permease | - |
OCUAc18_RS00515 (OCUAc18_00960) | 110450..110794 | - | 345 | Protein_98 | LysR substrate-binding domain-containing protein | - |
OCUAc18_RS00520 | 110833..112066 | - | 1234 | Protein_99 | IS3 family transposase | - |
OCUAc18_RS00525 (OCUAc18_01000) | 112125..112436 | - | 312 | WP_079281501.1 | LysR substrate-binding domain-containing protein | - |
OCUAc18_RS00530 | 112576..112674 | + | 99 | Protein_101 | IS5/IS1182 family transposase | - |
OCUAc18_RS00535 | 112706..112813 | - | 108 | Protein_102 | transposase domain-containing protein | - |
OCUAc18_RS00540 (OCUAc18_01010) | 112872..113135 | - | 264 | WP_000203952.1 | Txe/YoeB family addiction module toxin | Toxin |
OCUAc18_RS00545 (OCUAc18_01020) | 113122..113385 | - | 264 | WP_000557943.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
OCUAc18_RS00550 (OCUAc18_01030) | 113801..117148 | + | 3348 | WP_025467233.1 | DEAD/DEAH box helicase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10664.10 Da Isoelectric Point: 8.4894
>T39728 WP_000203952.1 NZ_AP024802:c113135-112872 [Acinetobacter baumannii]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY
Download Length: 264 bp
>T39728 NZ_AP024802:c113135-112872 [Acinetobacter baumannii]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGGAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
ATTCAATGTCGGTTCCATTACTAA
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGGAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
ATTCAATGTCGGTTCCATTACTAA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9841.04 Da Isoelectric Point: 5.5940
>AT39728 WP_000557943.1 NZ_AP024802:c113385-113122 [Acinetobacter baumannii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES
Download Length: 264 bp
>AT39728 NZ_AP024802:c113385-113122 [Acinetobacter baumannii]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGATAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGATAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2L2M0A2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S7WSW9 |