Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1915775..1915920 Replicon chromosome
Accession NZ_AP024792
Organism Klebsiella pneumoniae strain TUM12139

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1915811..1915913 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1915775..1915920 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J92_RS09350 (TUM12139_18010) 1910905..1912965 + 2061 WP_032422099.1 oligopeptidase B -
K6J92_RS09355 (TUM12139_18020) 1912969..1913628 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J92_RS09360 (TUM12139_18030) 1913707..1913937 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J92_RS09365 (TUM12139_18040) 1914050..1914424 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J92_RS09370 (TUM12139_18050) 1914428..1915297 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J92_RS09375 (TUM12139_18060) 1915314..1915652 + 339 WP_002911404.1 YebY family protein -
- 1915775..1915920 - 146 - - Antitoxin
- 1915811..1915913 + 103 - - Toxin
K6J92_RS09380 1916288..1916431 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J92_RS09385 (TUM12139_18070) 1916536..1917504 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J92_RS09390 (TUM12139_18080) 1917661..1918314 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J92_RS09395 (TUM12139_18090) 1918311..1918502 - 192 WP_002911395.1 YebW family protein -
K6J92_RS09400 (TUM12139_18100) 1918600..1918839 - 240 WP_002911393.1 YebV family protein -
K6J92_RS09405 (TUM12139_18110) 1918955..1920388 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39686 NZ_AP024792:1915811-1915913 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39686 NZ_AP024792:c1915920-1915775 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References