Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910492..1910637 Replicon chromosome
Accession NZ_AP024784
Organism Klebsiella pneumoniae strain TUM12137

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910528..1910630 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910492..1910637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K11_RS09340 (TUM12137_18010) 1905622..1907682 + 2061 WP_032422099.1 oligopeptidase B -
K6K11_RS09345 (TUM12137_18020) 1907686..1908345 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6K11_RS09350 (TUM12137_18030) 1908424..1908654 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6K11_RS09355 (TUM12137_18040) 1908767..1909141 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6K11_RS09360 (TUM12137_18050) 1909145..1910014 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6K11_RS09365 (TUM12137_18060) 1910031..1910369 + 339 WP_002911404.1 YebY family protein -
- 1910492..1910637 - 146 - - Antitoxin
- 1910528..1910630 + 103 - - Toxin
K6K11_RS09370 1911005..1911148 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6K11_RS09375 (TUM12137_18070) 1911253..1912221 - 969 WP_004151446.1 VirK/YbjX family protein -
K6K11_RS09380 (TUM12137_18080) 1912378..1913031 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6K11_RS09385 (TUM12137_18090) 1913028..1913219 - 192 WP_002911395.1 YebW family protein -
K6K11_RS09390 (TUM12137_18100) 1913317..1913556 - 240 WP_002911393.1 YebV family protein -
K6K11_RS09395 (TUM12137_18110) 1913672..1915105 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39640 NZ_AP024784:1910528-1910630 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39640 NZ_AP024784:c1910637-1910492 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References