Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1915776..1915921 Replicon chromosome
Accession NZ_AP024781
Organism Klebsiella pneumoniae strain TUM12136

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1915812..1915914 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1915776..1915921 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J90_RS09350 (TUM12136_18030) 1910906..1912966 + 2061 WP_032422099.1 oligopeptidase B -
K6J90_RS09355 (TUM12136_18040) 1912970..1913629 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J90_RS09360 (TUM12136_18050) 1913708..1913938 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J90_RS09365 (TUM12136_18060) 1914051..1914425 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J90_RS09370 (TUM12136_18070) 1914429..1915298 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J90_RS09375 (TUM12136_18080) 1915315..1915653 + 339 WP_002911404.1 YebY family protein -
- 1915776..1915921 - 146 - - Antitoxin
- 1915812..1915914 + 103 - - Toxin
K6J90_RS09380 1916289..1916432 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J90_RS09385 (TUM12136_18090) 1916537..1917505 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J90_RS09390 (TUM12136_18100) 1917662..1918315 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J90_RS09395 (TUM12136_18110) 1918312..1918503 - 192 WP_002911395.1 YebW family protein -
K6J90_RS09400 (TUM12136_18120) 1918601..1918840 - 240 WP_002911393.1 YebV family protein -
K6J90_RS09405 (TUM12136_18130) 1918956..1920389 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39621 NZ_AP024781:1915812-1915914 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39621 NZ_AP024781:c1915921-1915776 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References