Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1911130..1911275 Replicon chromosome
Accession NZ_AP024778
Organism Klebsiella pneumoniae strain TUM12135

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1911166..1911268 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1911130..1911275 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J93_RS09335 (TUM12135_18010) 1906260..1908320 + 2061 WP_032422099.1 oligopeptidase B -
K6J93_RS09340 (TUM12135_18020) 1908324..1908983 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J93_RS09345 (TUM12135_18030) 1909062..1909292 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J93_RS09350 (TUM12135_18040) 1909405..1909779 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J93_RS09355 (TUM12135_18050) 1909783..1910652 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J93_RS09360 (TUM12135_18060) 1910669..1911007 + 339 WP_002911404.1 YebY family protein -
- 1911130..1911275 - 146 - - Antitoxin
- 1911166..1911268 + 103 - - Toxin
K6J93_RS09365 1911643..1911786 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J93_RS09370 (TUM12135_18070) 1911891..1912859 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J93_RS09375 (TUM12135_18080) 1913016..1913669 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J93_RS09380 (TUM12135_18090) 1913666..1913857 - 192 WP_002911395.1 YebW family protein -
K6J93_RS09385 (TUM12135_18100) 1913955..1914194 - 240 WP_002911393.1 YebV family protein -
K6J93_RS09390 (TUM12135_18110) 1914310..1915743 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39602 NZ_AP024778:1911166-1911268 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39602 NZ_AP024778:c1911275-1911130 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References