Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1915774..1915919 Replicon chromosome
Accession NZ_AP024775
Organism Klebsiella pneumoniae strain TUM12134

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1915810..1915912 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1915774..1915919 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J97_RS09350 (TUM12134_18060) 1910904..1912964 + 2061 WP_032422099.1 oligopeptidase B -
K6J97_RS09355 (TUM12134_18070) 1912968..1913627 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J97_RS09360 (TUM12134_18080) 1913706..1913936 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J97_RS09365 (TUM12134_18090) 1914049..1914423 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J97_RS09370 (TUM12134_18100) 1914427..1915296 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J97_RS09375 (TUM12134_18110) 1915313..1915651 + 339 WP_002911404.1 YebY family protein -
- 1915774..1915919 - 146 - - Antitoxin
- 1915810..1915912 + 103 - - Toxin
K6J97_RS09380 1916287..1916430 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J97_RS09385 (TUM12134_18120) 1916535..1917503 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J97_RS09390 (TUM12134_18130) 1917660..1918313 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J97_RS09395 (TUM12134_18140) 1918310..1918501 - 192 WP_002911395.1 YebW family protein -
K6J97_RS09400 (TUM12134_18150) 1918599..1918838 - 240 WP_002911393.1 YebV family protein -
K6J97_RS09405 (TUM12134_18160) 1918954..1920387 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39583 NZ_AP024775:1915810-1915912 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39583 NZ_AP024775:c1915919-1915774 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References