Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910491..1910636 Replicon chromosome
Accession NZ_AP024769
Organism Klebsiella pneumoniae strain TUM12132

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910527..1910629 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910491..1910636 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J84_RS09340 (TUM12132_17990) 1905621..1907681 + 2061 WP_032422099.1 oligopeptidase B -
K6J84_RS09345 (TUM12132_18000) 1907685..1908344 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J84_RS09350 (TUM12132_18010) 1908423..1908653 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J84_RS09355 (TUM12132_18020) 1908766..1909140 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J84_RS09360 (TUM12132_18030) 1909144..1910013 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J84_RS09365 (TUM12132_18040) 1910030..1910368 + 339 WP_002911404.1 YebY family protein -
- 1910491..1910636 - 146 - - Antitoxin
- 1910527..1910629 + 103 - - Toxin
K6J84_RS09370 1911004..1911147 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J84_RS09375 (TUM12132_18050) 1911252..1912220 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J84_RS09380 (TUM12132_18060) 1912377..1913030 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J84_RS09385 (TUM12132_18070) 1913027..1913218 - 192 WP_002911395.1 YebW family protein -
K6J84_RS09390 (TUM12132_18080) 1913316..1913555 - 240 WP_002911393.1 YebV family protein -
K6J84_RS09395 (TUM12132_18090) 1913671..1915104 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39545 NZ_AP024769:1910527-1910629 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39545 NZ_AP024769:c1910636-1910491 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References