Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1916962..1917107 Replicon chromosome
Accession NZ_AP024766
Organism Klebsiella pneumoniae strain TUM12131

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1916998..1917100 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1916962..1917107 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J85_RS09355 (TUM12131_18010) 1912092..1914152 + 2061 WP_032422099.1 oligopeptidase B -
K6J85_RS09360 (TUM12131_18020) 1914156..1914815 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J85_RS09365 (TUM12131_18030) 1914894..1915124 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J85_RS09370 (TUM12131_18040) 1915237..1915611 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J85_RS09375 (TUM12131_18050) 1915615..1916484 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J85_RS09380 (TUM12131_18060) 1916501..1916839 + 339 WP_002911404.1 YebY family protein -
- 1916962..1917107 - 146 - - Antitoxin
- 1916998..1917100 + 103 - - Toxin
K6J85_RS09385 1917475..1917618 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J85_RS09390 (TUM12131_18070) 1917723..1918691 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J85_RS09395 (TUM12131_18080) 1918848..1919501 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J85_RS09400 (TUM12131_18090) 1919498..1919689 - 192 WP_002911395.1 YebW family protein -
K6J85_RS09405 (TUM12131_18100) 1919787..1920026 - 240 WP_002911393.1 YebV family protein -
K6J85_RS09410 (TUM12131_18110) 1920142..1921575 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39526 NZ_AP024766:1916998-1917100 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39526 NZ_AP024766:c1917107-1916962 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References