Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917738..1917883 Replicon chromosome
Accession NZ_AP024760
Organism Klebsiella pneumoniae strain TUM12129

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917774..1917876 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917738..1917883 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J88_RS09370 (TUM12129_18080) 1912868..1914928 + 2061 WP_032422099.1 oligopeptidase B -
K6J88_RS09375 (TUM12129_18090) 1914932..1915591 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J88_RS09380 (TUM12129_18100) 1915670..1915900 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J88_RS09385 (TUM12129_18110) 1916013..1916387 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J88_RS09390 (TUM12129_18120) 1916391..1917260 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J88_RS09395 (TUM12129_18130) 1917277..1917615 + 339 WP_002911404.1 YebY family protein -
- 1917738..1917883 - 146 - - Antitoxin
- 1917774..1917876 + 103 - - Toxin
K6J88_RS09400 1918251..1918394 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J88_RS09405 (TUM12129_18140) 1918499..1919467 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J88_RS09410 (TUM12129_18150) 1919624..1920277 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J88_RS09415 (TUM12129_18160) 1920274..1920465 - 192 WP_002911395.1 YebW family protein -
K6J88_RS09420 (TUM12129_18170) 1920563..1920802 - 240 WP_002911393.1 YebV family protein -
K6J88_RS09425 (TUM12129_18180) 1920918..1922351 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39488 NZ_AP024760:1917774-1917876 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39488 NZ_AP024760:c1917883-1917738 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References