Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1015174..1015319 Replicon chromosome
Accession NZ_AP024756
Organism Klebsiella pneumoniae strain TUM12128

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1015181..1015283 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1015174..1015319 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J96_RS05080 (TUM12128_09690) 1010706..1012139 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K6J96_RS05085 (TUM12128_09700) 1012255..1012494 + 240 WP_002911393.1 YebV family protein -
K6J96_RS05090 (TUM12128_09710) 1012592..1012783 + 192 WP_002911395.1 YebW family protein -
K6J96_RS05095 (TUM12128_09720) 1012780..1013433 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J96_RS05100 (TUM12128_09730) 1013590..1014558 + 969 WP_004151446.1 VirK/YbjX family protein -
K6J96_RS05105 1014663..1014806 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1015174..1015319 + 146 - - Antitoxin
- 1015181..1015283 - 103 - - Toxin
K6J96_RS05110 (TUM12128_09740) 1015442..1015780 - 339 WP_002911404.1 YebY family protein -
K6J96_RS05115 (TUM12128_09750) 1015797..1016666 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J96_RS05120 (TUM12128_09760) 1016670..1017044 - 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J96_RS05125 (TUM12128_09770) 1017157..1017387 + 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J96_RS05130 (TUM12128_09780) 1017466..1018125 + 660 WP_002911407.1 exodeoxyribonuclease X -
K6J96_RS05135 (TUM12128_09790) 1018129..1020189 - 2061 WP_032422099.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39466 NZ_AP024756:c1015283-1015181 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39466 NZ_AP024756:1015174-1015319 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References