Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1015174..1015319 | Replicon | chromosome |
| Accession | NZ_AP024756 | ||
| Organism | Klebsiella pneumoniae strain TUM12128 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1015181..1015283 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1015174..1015319 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J96_RS05080 (TUM12128_09690) | 1010706..1012139 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| K6J96_RS05085 (TUM12128_09700) | 1012255..1012494 | + | 240 | WP_002911393.1 | YebV family protein | - |
| K6J96_RS05090 (TUM12128_09710) | 1012592..1012783 | + | 192 | WP_002911395.1 | YebW family protein | - |
| K6J96_RS05095 (TUM12128_09720) | 1012780..1013433 | - | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| K6J96_RS05100 (TUM12128_09730) | 1013590..1014558 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| K6J96_RS05105 | 1014663..1014806 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 1015174..1015319 | + | 146 | - | - | Antitoxin |
| - | 1015181..1015283 | - | 103 | - | - | Toxin |
| K6J96_RS05110 (TUM12128_09740) | 1015442..1015780 | - | 339 | WP_002911404.1 | YebY family protein | - |
| K6J96_RS05115 (TUM12128_09750) | 1015797..1016666 | - | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| K6J96_RS05120 (TUM12128_09760) | 1016670..1017044 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| K6J96_RS05125 (TUM12128_09770) | 1017157..1017387 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| K6J96_RS05130 (TUM12128_09780) | 1017466..1018125 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| K6J96_RS05135 (TUM12128_09790) | 1018129..1020189 | - | 2061 | WP_032422099.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T39466 NZ_AP024756:c1015283-1015181 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT39466 NZ_AP024756:1015174-1015319 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT