Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1915918..1916063 Replicon chromosome
Accession NZ_AP024753
Organism Klebsiella pneumoniae strain TUM12127

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1915954..1916056 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1915918..1916063 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J87_RS09360 (TUM12127_18060) 1911048..1913108 + 2061 WP_032422099.1 oligopeptidase B -
K6J87_RS09365 (TUM12127_18070) 1913112..1913771 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J87_RS09370 (TUM12127_18080) 1913850..1914080 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J87_RS09375 (TUM12127_18090) 1914193..1914567 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J87_RS09380 (TUM12127_18100) 1914571..1915440 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J87_RS09385 (TUM12127_18110) 1915457..1915795 + 339 WP_002911404.1 YebY family protein -
- 1915918..1916063 - 146 - - Antitoxin
- 1915954..1916056 + 103 - - Toxin
K6J87_RS09390 1916431..1916574 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J87_RS09395 (TUM12127_18120) 1916679..1917647 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J87_RS09400 (TUM12127_18130) 1917804..1918457 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J87_RS09405 (TUM12127_18140) 1918454..1918645 - 192 WP_002911395.1 YebW family protein -
K6J87_RS09410 (TUM12127_18150) 1918743..1918982 - 240 WP_002911393.1 YebV family protein -
K6J87_RS09415 (TUM12127_18160) 1919098..1920531 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39450 NZ_AP024753:1915954-1916056 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39450 NZ_AP024753:c1916063-1915918 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References