Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1918386..1918531 Replicon chromosome
Accession NZ_AP024750
Organism Klebsiella pneumoniae strain TUM12126

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1918422..1918524 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1918386..1918531 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J82_RS09375 (TUM12126_18080) 1913516..1915576 + 2061 WP_032422099.1 oligopeptidase B -
K6J82_RS09380 (TUM12126_18090) 1915580..1916239 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6J82_RS09385 (TUM12126_18100) 1916318..1916548 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6J82_RS09390 (TUM12126_18110) 1916661..1917035 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6J82_RS09395 (TUM12126_18120) 1917039..1917908 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6J82_RS09400 (TUM12126_18130) 1917925..1918263 + 339 WP_002911404.1 YebY family protein -
- 1918386..1918531 - 146 - - Antitoxin
- 1918422..1918524 + 103 - - Toxin
K6J82_RS09405 1918899..1919042 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6J82_RS09410 (TUM12126_18140) 1919147..1920115 - 969 WP_004151446.1 VirK/YbjX family protein -
K6J82_RS09415 (TUM12126_18150) 1920272..1920925 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
K6J82_RS09420 (TUM12126_18160) 1920922..1921113 - 192 WP_002911395.1 YebW family protein -
K6J82_RS09425 (TUM12126_18170) 1921211..1921450 - 240 WP_002911393.1 YebV family protein -
K6J82_RS09430 (TUM12126_18180) 1921566..1922999 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T39431 NZ_AP024750:1918422-1918524 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT39431 NZ_AP024750:c1918531-1918386 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References