Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 654583..655148 Replicon chromosome
Accession NZ_AP024651
Organism Arthrobacter sp. StoSoilB20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDN85_RS03130 Protein ID WP_091553723.1
Coordinates 654583..654876 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDN85_RS03135 Protein ID WP_026548114.1
Coordinates 654873..655148 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDN85_RS03100 (StoSoilB20_06100) 649879..650508 + 630 WP_223944560.1 SipW-dependent-type signal peptide-containing protein -
LDN85_RS03105 (StoSoilB20_06110) 650512..651171 + 660 WP_223944561.1 SipW-dependent-type signal peptide-containing protein -
LDN85_RS03110 (StoSoilB20_06120) 651168..651692 + 525 WP_223944562.1 signal peptidase I -
LDN85_RS03115 651904..652113 - 210 WP_223944563.1 hypothetical protein -
LDN85_RS03120 (StoSoilB20_06130) 652400..652936 + 537 WP_223944564.1 hypothetical protein -
LDN85_RS03125 (StoSoilB20_06140) 653170..654459 + 1290 WP_144663349.1 adenylosuccinate synthase -
LDN85_RS03130 654583..654876 - 294 WP_091553723.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDN85_RS03135 (StoSoilB20_06160) 654873..655148 - 276 WP_026548114.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LDN85_RS03140 (StoSoilB20_06170) 655315..656775 + 1461 WP_223944565.1 MFS transporter -
LDN85_RS03145 (StoSoilB20_06180) 656786..657658 + 873 WP_223944566.1 SMP-30/gluconolactonase/LRE family protein -
LDN85_RS03150 (StoSoilB20_06190) 657753..657986 + 234 WP_026542327.1 DUF6480 family protein -
LDN85_RS03155 (StoSoilB20_06200) 658021..658941 + 921 WP_223944567.1 NADP-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11002.59 Da        Isoelectric Point: 9.8264

>T39145 WP_091553723.1 NZ_AP024651:c654876-654583 [Arthrobacter sp. StoSoilB20]
VTDSAGTSPSPWTIEVTSPALRGFRRLPEKAATAIIEFVTGPLAENPHRLSKPLTNELLGLRTARRGDYRVLFTLDLEEH
VLFVHRIEHRSDLYKPR

Download         Length: 294 bp

>T39145 NZ_AP024651:c654876-654583 [Arthrobacter sp. StoSoilB20]
GTGACCGATTCGGCCGGCACCAGTCCAAGTCCATGGACGATCGAAGTCACAAGCCCGGCGTTGCGCGGCTTCAGGCGCTT
ACCGGAAAAGGCCGCTACCGCGATCATTGAGTTCGTCACCGGACCCCTGGCGGAGAATCCGCATCGGCTCAGCAAGCCTT
TGACGAACGAACTCCTCGGACTCCGCACCGCTCGGCGAGGCGATTATCGGGTGCTCTTCACTCTGGACCTTGAAGAACAT
GTCCTTTTTGTCCACCGCATCGAACATCGATCTGATCTTTACAAACCCCGATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10060.18 Da        Isoelectric Point: 4.6736

>AT39145 WP_026548114.1 NZ_AP024651:c655148-654873 [Arthrobacter sp. StoSoilB20]
MRTVPLSEAKDKLSALVEEADSTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGIREDLDQAKRDIAAGNTTSGD
DLRREFGLPAR

Download         Length: 276 bp

>AT39145 NZ_AP024651:c655148-654873 [Arthrobacter sp. StoSoilB20]
ATGAGAACAGTGCCACTGAGTGAAGCCAAGGACAAGCTGTCCGCCTTGGTCGAAGAAGCAGACTCAACGCACGAGATCAT
TCAAATTACGCGACACGGCCATCCATCTGCCGTTCTCATGTCCGCGGACGACCTGGAATCTTTGCAGGAAACCATCCACT
GGCTCTCGCAGCCAGGTATCCGTGAAGACCTGGACCAGGCTAAACGCGACATCGCCGCGGGCAACACCACCAGCGGGGAC
GATCTCCGCCGGGAGTTTGGACTCCCGGCCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References