Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3410058..3411204 Replicon chromosome
Accession NZ_AP024618
Organism Shewanella carassii strain TUM17387

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag K5621_RS15490 Protein ID WP_221049682.1
Coordinates 3410058..3410804 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag K5621_RS15495 Protein ID WP_100142153.1
Coordinates 3410842..3411204 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5621_RS15465 (TUM17387_30180) 3406581..3406793 + 213 WP_157929023.1 hypothetical protein -
K5621_RS15470 (TUM17387_30190) 3406893..3407459 - 567 WP_100142149.1 phosphoribosyltransferase family protein -
K5621_RS15475 (TUM17387_30200) 3407867..3408592 + 726 WP_100142150.1 basic amino acid ABC transporter substrate-binding protein -
K5621_RS15480 (TUM17387_30210) 3408599..3409276 + 678 WP_044733837.1 amino acid ABC transporter permease -
K5621_RS15485 (TUM17387_30220) 3409269..3409994 + 726 WP_100142151.1 amino acid ABC transporter ATP-binding protein -
K5621_RS15490 (TUM17387_30230) 3410058..3410804 - 747 WP_221049682.1 RES family NAD+ phosphorylase Toxin
K5621_RS15495 (TUM17387_30240) 3410842..3411204 - 363 WP_100142153.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
K5621_RS15500 (TUM17387_30250) 3411388..3412041 + 654 WP_221049683.1 oxygen-insensitive NAD(P)H nitroreductase -
K5621_RS15505 (TUM17387_30260) 3412171..3412812 + 642 WP_100142155.1 DNA-J related domain-containing protein -
K5621_RS15510 (TUM17387_30270) 3412953..3413690 + 738 WP_100142156.1 DsbA family protein -
K5621_RS15515 (TUM17387_30280) 3413791..3416118 - 2328 WP_221049684.1 penicillin-binding protein 1B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(55-205)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(12-65)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 28932.76 Da        Isoelectric Point: 4.8782

>T38957 WP_221049682.1 NZ_AP024618:c3410804-3410058 [Shewanella carassii]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLFSVNIDARNCADLTLLQRQEVQQQLTHKSNY
AYTQALGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLR
DGQLPRPA

Download         Length: 747 bp

>T38957 NZ_AP024618:c3410804-3410058 [Shewanella carassii]
ATGGATTTTAGCGCGTTAGAGCCACAGGACTTTTTCCCTCGCCCCTACCTTGGCCGTGGTTATCGCCTGGTTGAATCTCA
AGAAGAAGCCGCCACTCTGAGTCTGGTGGATGATTTTGACGAACAGATGCTGCTCGAATCCCTGCTCGATGAGGTTAAAC
CGCCTTACCGGAGCGGGACAGAGCATTTACATTATCTGCTCAAGACCCCGTTTCGTTACCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACTATGGAAAGCTTCTTTTATGCCAGTGAGTCCTGGCAGACCTGCTTGGCCGAAGTCGCCTATTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCACTGCGCTCTGAGCATATGCTGTTCTCTGTGAATA
TTGATGCCCGCAATTGTGCCGATCTGACACTATTGCAGCGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
GCCTATACCCAAGCATTGGGGGCCTGGTTGTTGCAGCAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCTGAAGA
GGGCGTTAACCTGGCGCTGCACGATCCTCTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGTCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCGG
GACGGACAGTTGCCGCGTCCCGCCTGA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13198.26 Da        Isoelectric Point: 10.6250

>AT38957 WP_100142153.1 NZ_AP024618:c3411204-3410842 [Shewanella carassii]
MNTLEKANASEVLFKAFSNACRELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAMAGGEKAF
MRHWLNSPNKALNGTPKALLQTVVGLVSVNQYLDAMRGKV

Download         Length: 363 bp

>AT38957 NZ_AP024618:c3411204-3410842 [Shewanella carassii]
ATGAATACCCTAGAGAAAGCCAATGCCTCCGAGGTGTTATTCAAGGCATTTTCCAATGCTTGCCGAGAGTTACAACTTAC
CCAGGCCGAGGCCAGTCGCATCATAGGCGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGACT
CCAAGCAGGGGGAGTTGCAGTTGCAACTTATCCGTCTGTATCGTTCGCTGTATGCCATGGCGGGGGGAGAAAAAGCCTTT
ATGCGTCACTGGCTCAATAGCCCCAACAAGGCGCTGAATGGGACGCCAAAGGCTCTGTTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References