Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 2199914..2201071 | Replicon | chromosome |
| Accession | NZ_AP024617 | ||
| Organism | Shewanella algae strain TUM17386 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | K5631_RS09835 | Protein ID | WP_208170674.1 |
| Coordinates | 2199914..2200672 (-) | Length | 253 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | K5631_RS09840 | Protein ID | WP_025011540.1 |
| Coordinates | 2200709..2201071 (-) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5631_RS09810 (TUM17386_19290) | 2195131..2195697 | - | 567 | WP_025011535.1 | phosphoribosyltransferase family protein | - |
| K5631_RS09815 (TUM17386_19300) | 2196109..2196834 | + | 726 | WP_045283734.1 | basic amino acid ABC transporter substrate-binding protein | - |
| K5631_RS09820 (TUM17386_19310) | 2196841..2197518 | + | 678 | WP_208170678.1 | amino acid ABC transporter permease | - |
| K5631_RS09825 (TUM17386_19320) | 2197511..2198236 | + | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| K5631_RS09830 (TUM17386_19330) | 2198335..2199900 | + | 1566 | WP_208170676.1 | hypothetical protein | - |
| K5631_RS09835 (TUM17386_19340) | 2199914..2200672 | - | 759 | WP_208170674.1 | RES family NAD+ phosphorylase | Toxin |
| K5631_RS09840 (TUM17386_19350) | 2200709..2201071 | - | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| K5631_RS09845 (TUM17386_19360) | 2201304..2201957 | + | 654 | WP_093982133.1 | oxygen-insensitive NAD(P)H nitroreductase | - |
| K5631_RS09850 (TUM17386_19370) | 2202088..2202729 | + | 642 | WP_208170689.1 | DNA-J related domain-containing protein | - |
| K5631_RS09855 (TUM17386_19380) | 2202870..2203607 | + | 738 | WP_045283713.1 | DsbA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 253 a.a. Molecular weight: 29329.17 Da Isoelectric Point: 4.6168
>T38953 WP_208170674.1 NZ_AP024617:c2200672-2199914 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTH
KSNYTYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLK
DFLQDGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTH
KSNYTYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLK
DFLQDGQLPRPA
Download Length: 759 bp
>T38953 NZ_AP024617:c2200672-2199914 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGTCGTGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGT
ACTCTGTGGATATCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCAC
AAGTCGAACTATACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGC
CAGAGCCGAAGAGGGCGTTAATCTGGCGCTGCACGATCCTTTGGTATTGCAATCAACCGAGCCGCAGGAGTGTGAATACT
GGATCTGCCAAAGCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGTAGCATGCCATTGACCTGGTTTTTAAAA
GACTTTTTGCAGGACGGGCAGTTGCCACGTCCTGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGTCGTGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGT
ACTCTGTGGATATCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCAC
AAGTCGAACTATACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGC
CAGAGCCGAAGAGGGCGTTAATCTGGCGCTGCACGATCCTTTGGTATTGCAATCAACCGAGCCGCAGGAGTGTGAATACT
GGATCTGCCAAAGCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGTAGCATGCCATTGACCTGGTTTTTAAAA
GACTTTTTGCAGGACGGGCAGTTGCCACGTCCTGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT38953 WP_025011540.1 NZ_AP024617:c2201071-2200709 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT38953 NZ_AP024617:c2201071-2200709 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAACTTATCCGCCTGTATCGCTCGCTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTACAAACCGTGGTCGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAACTTATCCGCCTGTATCGCTCGCTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTACAAACCGTGGTCGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|