Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1121611..1122756 | Replicon | chromosome |
| Accession | NZ_AP024616 | ||
| Organism | Shewanella algae strain TUM17384 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | K5627_RS04995 | Protein ID | WP_054744620.1 |
| Coordinates | 1122010..1122756 (+) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | K5627_RS04990 | Protein ID | WP_025011540.1 |
| Coordinates | 1121611..1121973 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5627_RS04975 (TUM17384_09680) | 1119075..1119812 | - | 738 | WP_123115805.1 | thioredoxin domain-containing protein | - |
| K5627_RS04980 (TUM17384_09690) | 1119953..1120594 | - | 642 | WP_044735675.1 | DNA-J related domain-containing protein | - |
| K5627_RS04985 (TUM17384_09700) | 1120725..1121378 | - | 654 | WP_025886967.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| K5627_RS04990 (TUM17384_09710) | 1121611..1121973 | + | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| K5627_RS04995 (TUM17384_09720) | 1122010..1122756 | + | 747 | WP_054744620.1 | RES family NAD+ phosphorylase | Toxin |
| K5627_RS05000 (TUM17384_09730) | 1122770..1124335 | - | 1566 | WP_221059474.1 | hypothetical protein | - |
| K5627_RS05005 (TUM17384_09740) | 1124434..1125159 | - | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| K5627_RS05010 (TUM17384_09750) | 1125152..1125829 | - | 678 | WP_025011537.1 | amino acid ABC transporter permease | - |
| K5627_RS05015 (TUM17384_09760) | 1125836..1126561 | - | 726 | WP_045283734.1 | basic amino acid ABC transporter substrate-binding protein | - |
| K5627_RS05020 (TUM17384_09770) | 1126973..1127539 | + | 567 | WP_025011535.1 | phosphoribosyltransferase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28870.61 Da Isoelectric Point: 4.6112
>T38950 WP_054744620.1 NZ_AP024616:1122010-1122756 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
Download Length: 747 bp
>T38950 NZ_AP024616:1122010-1122756 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTAGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCTGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTAGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCTGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT38950 WP_025011540.1 NZ_AP024616:1121611-1121973 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT38950 NZ_AP024616:1121611-1121973 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGCTGTATGCCATCGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTACAAACCGTGGTAGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGCTGTATGCCATCGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTACAAACCGTGGTAGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|