Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1115464..1116609 | Replicon | chromosome |
| Accession | NZ_AP024613 | ||
| Organism | Shewanella algae strain TUM17379 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | K5628_RS05020 | Protein ID | WP_208146423.1 |
| Coordinates | 1115863..1116609 (+) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | K5628_RS05015 | Protein ID | WP_025011540.1 |
| Coordinates | 1115464..1115826 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5628_RS05000 (TUM17379_09740) | 1112928..1113665 | - | 738 | WP_123115805.1 | thioredoxin domain-containing protein | - |
| K5628_RS05005 (TUM17379_09750) | 1113806..1114447 | - | 642 | WP_208146444.1 | DNA-J related domain-containing protein | - |
| K5628_RS05010 (TUM17379_09760) | 1114578..1115231 | - | 654 | WP_045283714.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| K5628_RS05015 (TUM17379_09770) | 1115464..1115826 | + | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| K5628_RS05020 (TUM17379_09780) | 1115863..1116609 | + | 747 | WP_208146423.1 | RES family NAD+ phosphorylase | Toxin |
| K5628_RS05025 (TUM17379_09790) | 1116623..1118188 | - | 1566 | WP_208146424.1 | hypothetical protein | - |
| K5628_RS05030 (TUM17379_09800) | 1118287..1119012 | - | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| K5628_RS05035 (TUM17379_09810) | 1119005..1119682 | - | 678 | WP_025011537.1 | amino acid ABC transporter permease | - |
| K5628_RS05040 (TUM17379_09820) | 1119689..1120414 | - | 726 | WP_045283734.1 | basic amino acid ABC transporter substrate-binding protein | - |
| K5628_RS05045 (TUM17379_09830) | 1120826..1121392 | + | 567 | WP_025011535.1 | phosphoribosyltransferase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28839.59 Da Isoelectric Point: 4.6112
>T38941 WP_208146423.1 NZ_AP024613:1115863-1116609 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGPEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGPEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
Download Length: 747 bp
>T38941 NZ_AP024613:1115863-1116609 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCCGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCCGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCCTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCCGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCCGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT38941 WP_025011540.1 NZ_AP024613:1115464-1115826 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT38941 NZ_AP024613:1115464-1115826 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAGCTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|