Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1125521..1126666 | Replicon | chromosome |
| Accession | NZ_AP024612 | ||
| Organism | Shewanella algae strain TUM17378 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | K5624_RS05010 | Protein ID | WP_045283715.1 |
| Coordinates | 1125920..1126666 (+) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | K5624_RS05005 | Protein ID | WP_025011540.1 |
| Coordinates | 1125521..1125883 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5624_RS04990 (TUM17378_09710) | 1122986..1123723 | - | 738 | WP_045283713.1 | DsbA family protein | - |
| K5624_RS04995 (TUM17378_09720) | 1123864..1124505 | - | 642 | WP_028780153.1 | DNA-J related domain-containing protein | - |
| K5624_RS05000 (TUM17378_09730) | 1124636..1125289 | - | 654 | WP_045283714.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| K5624_RS05005 (TUM17378_09740) | 1125521..1125883 | + | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| K5624_RS05010 (TUM17378_09750) | 1125920..1126666 | + | 747 | WP_045283715.1 | RES family NAD+ phosphorylase | Toxin |
| K5624_RS05015 (TUM17378_09760) | 1126680..1128245 | - | 1566 | WP_144380062.1 | hypothetical protein | - |
| K5624_RS05020 (TUM17378_09770) | 1128344..1129069 | - | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| K5624_RS05025 (TUM17378_09780) | 1129062..1129739 | - | 678 | WP_025011537.1 | amino acid ABC transporter permease | - |
| K5624_RS05030 (TUM17378_09790) | 1129746..1130471 | - | 726 | WP_045283734.1 | basic amino acid ABC transporter substrate-binding protein | - |
| K5624_RS05035 (TUM17378_09800) | 1130883..1131449 | + | 567 | WP_025011535.1 | phosphoribosyltransferase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28826.60 Da Isoelectric Point: 4.6800
>T38937 WP_045283715.1 NZ_AP024612:1125920-1126666 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
Download Length: 747 bp
>T38937 NZ_AP024612:1125920-1126666 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTATTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACTTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCTGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTTGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGGGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAATCTGGCGCTGCACGATCCTTTGGTATTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACTTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCTGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT38937 WP_025011540.1 NZ_AP024612:1125521-1125883 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT38937 NZ_AP024612:1125521-1125883 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAGAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAGAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|