Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1098611..1099756 | Replicon | chromosome |
| Accession | NZ_AP024610 | ||
| Organism | Shewanella algae strain TUM4442 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | K5626_RS04900 | Protein ID | WP_221052662.1 |
| Coordinates | 1099010..1099756 (+) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | K5626_RS04895 | Protein ID | WP_025011540.1 |
| Coordinates | 1098611..1098973 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5626_RS04880 (TUM4442_09590) | 1096075..1096812 | - | 738 | WP_221052660.1 | DsbA family protein | - |
| K5626_RS04885 (TUM4442_09600) | 1096953..1097594 | - | 642 | WP_129979284.1 | DNA-J related domain-containing protein | - |
| K5626_RS04890 (TUM4442_09610) | 1097725..1098378 | - | 654 | WP_221052661.1 | oxygen-insensitive NAD(P)H nitroreductase | - |
| K5626_RS04895 (TUM4442_09620) | 1098611..1098973 | + | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| K5626_RS04900 (TUM4442_09630) | 1099010..1099756 | + | 747 | WP_221052662.1 | RES family NAD+ phosphorylase | Toxin |
| K5626_RS04905 (TUM4442_09640) | 1099771..1101336 | - | 1566 | WP_221052663.1 | hypothetical protein | - |
| K5626_RS04910 (TUM4442_09650) | 1101435..1102160 | - | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| K5626_RS04915 (TUM4442_09660) | 1102153..1102830 | - | 678 | WP_025011537.1 | amino acid ABC transporter permease | - |
| K5626_RS04920 (TUM4442_09670) | 1102837..1103562 | - | 726 | WP_221052884.1 | basic amino acid ABC transporter substrate-binding protein | - |
| K5626_RS04925 (TUM4442_09680) | 1103974..1104540 | + | 567 | WP_025011535.1 | phosphoribosyltransferase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28858.74 Da Isoelectric Point: 4.9912
>T38934 WP_221052662.1 NZ_AP024610:1099010-1099756 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLFSVNIDACHCADLTLLQRQEVQQQLTHKSNY
AYTQALGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLKDFLR
DGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLFSVNIDACHCADLTLLQRQEVQQQLTHKSNY
AYTQALGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSAAKVAFSRRNSRSMPLTWFLKDFLR
DGQLPRPA
Download Length: 747 bp
>T38934 NZ_AP024610:1099010-1099756 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTCGAATCCCTGCTCGATGAGGTTAAAC
CGCCTTACCGGAGCGGGACTGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTACCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACTATGGAAAGCTTCTTTTATGCTAGTGAGTCCTGGCAGACCTGCTTGGCCGAAGTCGCCTATTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCACTGCGCTCTGAGCATATGCTGTTCTCTGTGAATA
TTGATGCCTGCCATTGTGCCGATCTGACACTATTGCAGCGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
GCCTATACCCAAGCATTGGGGGCCTGGTTGTTGCAGCAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCTGAAGA
GGGCGTTAACCTGGCGCTGCACGATCCTCTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCGG
GACGGGCAGTTGCCGCGTCCCGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCCGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTCGAATCCCTGCTCGATGAGGTTAAAC
CGCCTTACCGGAGCGGGACTGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTACCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACTATGGAAAGCTTCTTTTATGCTAGTGAGTCCTGGCAGACCTGCTTGGCCGAAGTCGCCTATTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCACTGCGCTCTGAGCATATGCTGTTCTCTGTGAATA
TTGATGCCTGCCATTGTGCCGATCTGACACTATTGCAGCGGCAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
GCCTATACCCAAGCATTGGGGGCCTGGTTGTTGCAGCAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCTGAAGA
GGGCGTTAACCTGGCGCTGCACGATCCTCTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGCCAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCGG
GACGGGCAGTTGCCGCGTCCCGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT38934 WP_025011540.1 NZ_AP024610:1098611-1098973 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT38934 NZ_AP024610:1098611-1098973 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAAAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|