Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 93063..93703 Replicon chromosome
Accession NZ_AP024597
Organism Stygiolobus caldivivus strain KN-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KN1_RS00435 Protein ID WP_221288673.1
Coordinates 93317..93703 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KN1_RS00430 Protein ID WP_221290405.1
Coordinates 93063..93320 (+) Length 86 a.a.

Genomic Context


KN1_RS00405KN1_RS00410KN1_RS00420KN1_RS00425KN1_RS00430KN1_RS00435KN1_RS00445KN1_RS00450KN1_RS00415KN1_RS00440KN1_RS00455
Location: 88795..89157 (363 bp)
Type: Others
Protein ID: WP_221288666.1
Location: 89133..89507 (375 bp)
Type: Others
Protein ID: WP_221288668.1
Location: 90920..92572 (1653 bp)
Type: Others
Protein ID: WP_221288671.1
Location: 92578..92832 (255 bp)
Type: Others
Protein ID: WP_221288672.1
Location: 93063..93320 (258 bp)
Type: Antitoxin
Protein ID: WP_221290405.1
Location: 93317..93703 (387 bp)
Type: Toxin
Protein ID: WP_221288673.1
Location: 95158..95997 (840 bp)
Type: Others
Protein ID: WP_221288675.1
Location: 96382..96789 (408 bp)
Type: Others
Protein ID: WP_221288676.1
Location: 89958..90692 (735 bp)
Type: Others
Protein ID: WP_221288670.1
Location: 94375..94815 (441 bp)
Type: Others
Protein ID: WP_221288674.1
Location: 97410..98399 (990 bp)
Type: Others
Protein ID: WP_221288677.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KN1_RS00405 (KN1_00920)88795..89157+363WP_221288666.1ribbon-helix-helix domain-containing protein-
KN1_RS00410 (KN1_00930)89133..89507+375WP_221288668.1clan AA aspartic protease-
KN1_RS00415 (KN1_00940)89958..90692-735WP_221288670.1endonuclease NucS-
KN1_RS00420 (KN1_00950)90920..92572+1653WP_221288671.1DUF87 domain-containing protein-
KN1_RS00425 (KN1_00960)92578..92832+255WP_221288672.1hypothetical protein-
KN1_RS00430 (KN1_00970)93063..93320+258WP_221290405.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
KN1_RS00435 (KN1_00980)93317..93703+387WP_221288673.1type II toxin-antitoxin system VapC family toxinToxin
KN1_RS00440 (KN1_00990)94375..94815-441WP_221288674.1hypothetical protein-
KN1_RS00445 (KN1_01000)95158..95997+840WP_221288675.1hypothetical protein-
KN1_RS00450 (KN1_01010)96382..96789+408WP_221288676.1rhodanese-like domain-containing protein-
KN1_RS00455 (KN1_01020)97410..98399-990WP_221288677.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-120)

Antitoxin

(4-46)


Sequences


Toxin        


Download         Length: 129 a.a.        Molecular weight: 14740.12 Da        Isoelectric Point: 4.6190

>T38904 WP_221288673.1 NZ_AP024597:93317-93703 [Stygiolobus caldivivus]
VIFLDANFLIYLNLGVRGVEEFYYKLLSEENTALDPLVIDEVVYVSKKKYGVKYEDTLEFLDNVVLPYSVVFPITVEEYK
RAKDIMLVGLKPSDAFHVAVMLNNSVLRVVSEDADFDKVKGVQRVWLR

Download         Length: 387 bp

>T38904 NZ_AP024597:93317-93703 [Stygiolobus caldivivus]
GTGATTTTCCTCGACGCTAACTTCCTCATCTATTTGAACTTAGGTGTAAGAGGAGTAGAAGAGTTTTATTATAAGCTCCT
CAGTGAGGAAAATACTGCACTGGACCCCTTAGTTATTGATGAAGTAGTCTATGTGTCTAAGAAGAAATACGGTGTGAAGT
ATGAAGACACTTTGGAGTTTTTAGACAATGTAGTCCTCCCGTACTCTGTAGTATTCCCTATAACGGTTGAGGAGTATAAG
AGGGCGAAGGACATAATGCTGGTGGGCTTAAAGCCATCCGACGCTTTCCATGTAGCTGTTATGTTAAATAACTCCGTCTT
AAGGGTCGTCAGTGAAGACGCAGACTTCGATAAAGTGAAGGGTGTCCAAAGGGTTTGGCTTAGATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9640.39 Da        Isoelectric Point: 8.4281

>AT38904 WP_221290405.1 NZ_AP024597:93063-93320 [Stygiolobus caldivivus]
MALKVEVGKKGYVIIPKSIRDLVGIKEGDVLILRVTDGKIILEPERKVDLESLRKYMEGHKKKISYAKEAKLGELANISL
EEEFE

Download         Length: 258 bp

>AT38904 NZ_AP024597:93063-93320 [Stygiolobus caldivivus]
TTGGCCCTGAAGGTGGAAGTCGGGAAAAAAGGTTACGTAATAATCCCTAAAAGTATAAGGGACCTCGTCGGGATTAAAGA
GGGGGACGTACTAATACTACGTGTCACAGACGGGAAAATTATCCTCGAGCCTGAAAGGAAAGTCGACCTCGAGTCCTTGA
GGAAATATATGGAGGGACACAAGAAGAAAATATCGTATGCAAAGGAGGCTAAGTTAGGTGAGCTGGCTAATATAAGCCTA
GAGGAGGAATTTGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References