Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN-AbrB |
Location | 93063..93703 | Replicon | chromosome |
Accession | NZ_AP024597 | ||
Organism | Stygiolobus caldivivus strain KN-1 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | KN1_RS00435 | Protein ID | WP_221288673.1 |
Coordinates | 93317..93703 (+) | Length | 129 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | KN1_RS00430 | Protein ID | WP_221290405.1 |
Coordinates | 93063..93320 (+) | Length | 86 a.a. |
Genomic Context
Location: 88795..89157 (363 bp)
Type: Others
Protein ID: WP_221288666.1
Type: Others
Protein ID: WP_221288666.1
Location: 89133..89507 (375 bp)
Type: Others
Protein ID: WP_221288668.1
Type: Others
Protein ID: WP_221288668.1
Location: 90920..92572 (1653 bp)
Type: Others
Protein ID: WP_221288671.1
Type: Others
Protein ID: WP_221288671.1
Location: 92578..92832 (255 bp)
Type: Others
Protein ID: WP_221288672.1
Type: Others
Protein ID: WP_221288672.1
Location: 93063..93320 (258 bp)
Type: Antitoxin
Protein ID: WP_221290405.1
Type: Antitoxin
Protein ID: WP_221290405.1
Location: 93317..93703 (387 bp)
Type: Toxin
Protein ID: WP_221288673.1
Type: Toxin
Protein ID: WP_221288673.1
Location: 95158..95997 (840 bp)
Type: Others
Protein ID: WP_221288675.1
Type: Others
Protein ID: WP_221288675.1
Location: 96382..96789 (408 bp)
Type: Others
Protein ID: WP_221288676.1
Type: Others
Protein ID: WP_221288676.1
Location: 89958..90692 (735 bp)
Type: Others
Protein ID: WP_221288670.1
Type: Others
Protein ID: WP_221288670.1
Location: 94375..94815 (441 bp)
Type: Others
Protein ID: WP_221288674.1
Type: Others
Protein ID: WP_221288674.1
Location: 97410..98399 (990 bp)
Type: Others
Protein ID: WP_221288677.1
Type: Others
Protein ID: WP_221288677.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KN1_RS00405 (KN1_00920) | 88795..89157 | + | 363 | WP_221288666.1 | ribbon-helix-helix domain-containing protein | - |
KN1_RS00410 (KN1_00930) | 89133..89507 | + | 375 | WP_221288668.1 | clan AA aspartic protease | - |
KN1_RS00415 (KN1_00940) | 89958..90692 | - | 735 | WP_221288670.1 | endonuclease NucS | - |
KN1_RS00420 (KN1_00950) | 90920..92572 | + | 1653 | WP_221288671.1 | DUF87 domain-containing protein | - |
KN1_RS00425 (KN1_00960) | 92578..92832 | + | 255 | WP_221288672.1 | hypothetical protein | - |
KN1_RS00430 (KN1_00970) | 93063..93320 | + | 258 | WP_221290405.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
KN1_RS00435 (KN1_00980) | 93317..93703 | + | 387 | WP_221288673.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
KN1_RS00440 (KN1_00990) | 94375..94815 | - | 441 | WP_221288674.1 | hypothetical protein | - |
KN1_RS00445 (KN1_01000) | 95158..95997 | + | 840 | WP_221288675.1 | hypothetical protein | - |
KN1_RS00450 (KN1_01010) | 96382..96789 | + | 408 | WP_221288676.1 | rhodanese-like domain-containing protein | - |
KN1_RS00455 (KN1_01020) | 97410..98399 | - | 990 | WP_221288677.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14740.12 Da Isoelectric Point: 4.6190
>T38904 WP_221288673.1 NZ_AP024597:93317-93703 [Stygiolobus caldivivus]
VIFLDANFLIYLNLGVRGVEEFYYKLLSEENTALDPLVIDEVVYVSKKKYGVKYEDTLEFLDNVVLPYSVVFPITVEEYK
RAKDIMLVGLKPSDAFHVAVMLNNSVLRVVSEDADFDKVKGVQRVWLR
VIFLDANFLIYLNLGVRGVEEFYYKLLSEENTALDPLVIDEVVYVSKKKYGVKYEDTLEFLDNVVLPYSVVFPITVEEYK
RAKDIMLVGLKPSDAFHVAVMLNNSVLRVVSEDADFDKVKGVQRVWLR
Download Length: 387 bp
>T38904 NZ_AP024597:93317-93703 [Stygiolobus caldivivus]
GTGATTTTCCTCGACGCTAACTTCCTCATCTATTTGAACTTAGGTGTAAGAGGAGTAGAAGAGTTTTATTATAAGCTCCT
CAGTGAGGAAAATACTGCACTGGACCCCTTAGTTATTGATGAAGTAGTCTATGTGTCTAAGAAGAAATACGGTGTGAAGT
ATGAAGACACTTTGGAGTTTTTAGACAATGTAGTCCTCCCGTACTCTGTAGTATTCCCTATAACGGTTGAGGAGTATAAG
AGGGCGAAGGACATAATGCTGGTGGGCTTAAAGCCATCCGACGCTTTCCATGTAGCTGTTATGTTAAATAACTCCGTCTT
AAGGGTCGTCAGTGAAGACGCAGACTTCGATAAAGTGAAGGGTGTCCAAAGGGTTTGGCTTAGATAA
GTGATTTTCCTCGACGCTAACTTCCTCATCTATTTGAACTTAGGTGTAAGAGGAGTAGAAGAGTTTTATTATAAGCTCCT
CAGTGAGGAAAATACTGCACTGGACCCCTTAGTTATTGATGAAGTAGTCTATGTGTCTAAGAAGAAATACGGTGTGAAGT
ATGAAGACACTTTGGAGTTTTTAGACAATGTAGTCCTCCCGTACTCTGTAGTATTCCCTATAACGGTTGAGGAGTATAAG
AGGGCGAAGGACATAATGCTGGTGGGCTTAAAGCCATCCGACGCTTTCCATGTAGCTGTTATGTTAAATAACTCCGTCTT
AAGGGTCGTCAGTGAAGACGCAGACTTCGATAAAGTGAAGGGTGTCCAAAGGGTTTGGCTTAGATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9640.39 Da Isoelectric Point: 8.4281
>AT38904 WP_221290405.1 NZ_AP024597:93063-93320 [Stygiolobus caldivivus]
MALKVEVGKKGYVIIPKSIRDLVGIKEGDVLILRVTDGKIILEPERKVDLESLRKYMEGHKKKISYAKEAKLGELANISL
EEEFE
MALKVEVGKKGYVIIPKSIRDLVGIKEGDVLILRVTDGKIILEPERKVDLESLRKYMEGHKKKISYAKEAKLGELANISL
EEEFE
Download Length: 258 bp
>AT38904 NZ_AP024597:93063-93320 [Stygiolobus caldivivus]
TTGGCCCTGAAGGTGGAAGTCGGGAAAAAAGGTTACGTAATAATCCCTAAAAGTATAAGGGACCTCGTCGGGATTAAAGA
GGGGGACGTACTAATACTACGTGTCACAGACGGGAAAATTATCCTCGAGCCTGAAAGGAAAGTCGACCTCGAGTCCTTGA
GGAAATATATGGAGGGACACAAGAAGAAAATATCGTATGCAAAGGAGGCTAAGTTAGGTGAGCTGGCTAATATAAGCCTA
GAGGAGGAATTTGAGTGA
TTGGCCCTGAAGGTGGAAGTCGGGAAAAAAGGTTACGTAATAATCCCTAAAAGTATAAGGGACCTCGTCGGGATTAAAGA
GGGGGACGTACTAATACTACGTGTCACAGACGGGAAAATTATCCTCGAGCCTGAAAGGAAAGTCGACCTCGAGTCCTTGA
GGAAATATATGGAGGGACACAAGAAGAAAATATCGTATGCAAAGGAGGCTAAGTTAGGTGAGCTGGCTAATATAAGCCTA
GAGGAGGAATTTGAGTGA