Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910315..1910459 Replicon chromosome
Accession NZ_AP024592
Organism Klebsiella variicola strain JCM 12419

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910351..1910453 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910315..1910459 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI238_RS09180 (KLVA_17670) 1905445..1907505 + 2061 WP_012541258.1 oligopeptidase B -
KI238_RS09185 (KLVA_17680) 1907509..1908168 - 660 WP_012541259.1 exodeoxyribonuclease X -
KI238_RS09190 (KLVA_17690) 1908247..1908477 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KI238_RS09195 (KLVA_17700) 1908591..1908965 + 375 WP_012541261.1 CopC domain-containing protein YobA -
KI238_RS09200 (KLVA_17710) 1908969..1909838 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
KI238_RS09205 (KLVA_17720) 1909855..1910193 + 339 WP_008804271.1 YebY family protein -
- 1910315..1910459 - 145 - - Antitoxin
- 1910351..1910453 + 103 - - Toxin
KI238_RS09210 1910838..1910981 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
KI238_RS09215 (KLVA_17740) 1911085..1912053 - 969 WP_162493241.1 VirK/YbjX family protein -
KI238_RS09220 (KLVA_17750) 1912210..1912863 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
KI238_RS09225 (KLVA_17760) 1912860..1913051 - 192 WP_002911395.1 YebW family protein -
KI238_RS09230 (KLVA_17770) 1913149..1913388 - 240 WP_002911393.1 YebV family protein -
KI238_RS09235 (KLVA_17780) 1913504..1914937 - 1434 WP_046881617.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T38884 NZ_AP024592:1910351-1910453 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT38884 NZ_AP024592:c1910459-1910315 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References