Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1994378..1994523 | Replicon | chromosome |
| Accession | NZ_AP024579 | ||
| Organism | Klebsiella pneumoniae strain KpWEA4-2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1994414..1994516 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1994378..1994523 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6443_RS09630 (MAKP6SUB2_18560) | 1989508..1991568 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| L6443_RS09635 (MAKP6SUB2_18570) | 1991572..1992231 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| L6443_RS09640 (MAKP6SUB2_18580) | 1992310..1992540 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| L6443_RS09645 (MAKP6SUB2_18590) | 1992653..1993027 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| L6443_RS09650 (MAKP6SUB2_18600) | 1993031..1993900 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| L6443_RS09655 (MAKP6SUB2_18610) | 1993917..1994255 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1994378..1994523 | - | 146 | - | - | Antitoxin |
| - | 1994414..1994516 | + | 103 | - | - | Toxin |
| L6443_RS09660 | 1994891..1995034 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| L6443_RS09665 (MAKP6SUB2_18620) | 1995139..1996107 | - | 969 | WP_162472361.1 | VirK/YbjX family protein | - |
| L6443_RS09670 (MAKP6SUB2_18630) | 1996264..1996917 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| L6443_RS09675 (MAKP6SUB2_18640) | 1996914..1997105 | - | 192 | WP_002911395.1 | YebW family protein | - |
| L6443_RS09680 (MAKP6SUB2_18650) | 1997203..1997442 | - | 240 | WP_002911393.1 | YebV family protein | - |
| L6443_RS09685 (MAKP6SUB2_18660) | 1997558..1998991 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T38846 NZ_AP024579:1994414-1994516 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT38846 NZ_AP024579:c1994523-1994378 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
