Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1888568..1888713 | Replicon | chromosome |
| Accession | NZ_AP024576 | ||
| Organism | Klebsiella pneumoniae strain KpWEA4-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1888604..1888706 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1888568..1888713 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6441_RS09105 (MAKP6SUB1_17550) | 1883698..1885758 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| L6441_RS09110 (MAKP6SUB1_17560) | 1885762..1886421 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| L6441_RS09115 (MAKP6SUB1_17570) | 1886500..1886730 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| L6441_RS09120 (MAKP6SUB1_17580) | 1886843..1887217 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| L6441_RS09125 (MAKP6SUB1_17590) | 1887221..1888090 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| L6441_RS09130 (MAKP6SUB1_17600) | 1888107..1888445 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1888568..1888713 | - | 146 | - | - | Antitoxin |
| - | 1888604..1888706 | + | 103 | - | - | Toxin |
| L6441_RS09135 | 1889081..1889224 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| L6441_RS09140 (MAKP6SUB1_17610) | 1889329..1890297 | - | 969 | WP_162472361.1 | VirK/YbjX family protein | - |
| L6441_RS09145 (MAKP6SUB1_17620) | 1890454..1891107 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| L6441_RS09150 (MAKP6SUB1_17630) | 1891104..1891295 | - | 192 | WP_002911395.1 | YebW family protein | - |
| L6441_RS09155 (MAKP6SUB1_17640) | 1891393..1891632 | - | 240 | WP_002911393.1 | YebV family protein | - |
| L6441_RS09160 (MAKP6SUB1_17650) | 1891748..1893181 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T38827 NZ_AP024576:1888604-1888706 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT38827 NZ_AP024576:c1888713-1888568 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
