Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1885862..1886007 Replicon chromosome
Accession NZ_AP024572
Organism Klebsiella pneumoniae strain KpWEA3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1885898..1886000 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1885862..1886007 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6447_RS09090 (MAKP5_17460) 1880992..1883052 + 2061 WP_004151449.1 oligopeptidase B -
L6447_RS09095 (MAKP5_17470) 1883056..1883715 - 660 WP_021440386.1 exodeoxyribonuclease X -
L6447_RS09100 (MAKP5_17480) 1883794..1884024 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L6447_RS09105 (MAKP5_17490) 1884137..1884511 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L6447_RS09110 (MAKP5_17500) 1884515..1885384 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
L6447_RS09115 (MAKP5_17510) 1885401..1885739 + 339 WP_002911404.1 YebY family protein -
- 1885862..1886007 - 146 - - Antitoxin
- 1885898..1886000 + 103 - - Toxin
L6447_RS09120 1886375..1886518 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L6447_RS09125 (MAKP5_17520) 1886623..1887591 - 969 WP_162472361.1 VirK/YbjX family protein -
L6447_RS09130 (MAKP5_17530) 1887748..1888401 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
L6447_RS09135 (MAKP5_17540) 1888398..1888589 - 192 WP_002911395.1 YebW family protein -
L6447_RS09140 (MAKP5_17550) 1888687..1888926 - 240 WP_002911393.1 YebV family protein -
L6447_RS09145 (MAKP5_17560) 1889042..1890475 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T38808 NZ_AP024572:1885898-1886000 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT38808 NZ_AP024572:c1886007-1885862 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References