Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1885863..1886008 Replicon chromosome
Accession NZ_AP024570
Organism Klebsiella pneumoniae strain KpWEA2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1885899..1886001 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1885863..1886008 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6448_RS09085 (MAKP4_17500) 1880993..1883053 + 2061 WP_004151449.1 oligopeptidase B -
L6448_RS09090 (MAKP4_17510) 1883057..1883716 - 660 WP_021440386.1 exodeoxyribonuclease X -
L6448_RS09095 (MAKP4_17520) 1883795..1884025 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L6448_RS09100 (MAKP4_17530) 1884138..1884512 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L6448_RS09105 (MAKP4_17540) 1884516..1885385 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
L6448_RS09110 (MAKP4_17550) 1885402..1885740 + 339 WP_002911404.1 YebY family protein -
- 1885863..1886008 - 146 - - Antitoxin
- 1885899..1886001 + 103 - - Toxin
L6448_RS09115 1886376..1886519 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L6448_RS09120 (MAKP4_17560) 1886624..1887592 - 969 WP_162472361.1 VirK/YbjX family protein -
L6448_RS09125 (MAKP4_17570) 1887749..1888402 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
L6448_RS09130 (MAKP4_17580) 1888399..1888590 - 192 WP_002911395.1 YebW family protein -
L6448_RS09135 (MAKP4_17590) 1888688..1888927 - 240 WP_002911393.1 YebV family protein -
L6448_RS09140 (MAKP4_17600) 1889043..1890476 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T38789 NZ_AP024570:1885899-1886001 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT38789 NZ_AP024570:c1886008-1885863 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References