Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2416902..2417560 Replicon chromosome
Accession NZ_AP024563
Organism Allochromatium tepidum strain NZ

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Atep_RS11665 Protein ID WP_213378679.1
Coordinates 2417138..2417560 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Atep_RS11660 Protein ID WP_213378678.1
Coordinates 2416902..2417141 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Atep_RS11630 (Atep_22580) 2411978..2412700 + 723 WP_213378673.1 UMP kinase -
Atep_RS11635 (Atep_22590) 2412705..2413262 + 558 WP_213378674.1 ribosome recycling factor -
Atep_RS11640 (Atep_22600) 2413300..2414091 + 792 WP_213378675.1 isoprenyl transferase -
Atep_RS11645 (Atep_22610) 2414075..2414923 + 849 WP_213378676.1 phosphatidate cytidylyltransferase -
Atep_RS11650 (Atep_22620) 2414937..2416124 + 1188 WP_213378677.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
Atep_RS11655 (Atep_22630) 2416354..2416866 + 513 WP_272876288.1 transposase -
Atep_RS11660 (Atep_22640) 2416902..2417141 + 240 WP_213378678.1 Arc family DNA-binding protein Antitoxin
Atep_RS11665 (Atep_22650) 2417138..2417560 + 423 WP_213378679.1 type II toxin-antitoxin system VapC family toxin Toxin
Atep_RS11670 (Atep_22660) 2417756..2419126 + 1371 WP_213381629.1 RIP metalloprotease RseP -
Atep_RS11675 (Atep_22670) 2419205..2421535 + 2331 WP_213378680.1 outer membrane protein assembly factor BamA -
Atep_RS11680 (Atep_22680) 2421551..2422108 + 558 WP_236786165.1 OmpH family outer membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin

Arc-like DNA binding domain

(5-46)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14941.05 Da        Isoelectric Point: 4.5657

>T38751 WP_213378679.1 NZ_AP024563:2417138-2417560 [Allochromatium tepidum]
MIILDTNVVSEPLRPRGSDKVTAWLDAQAPETLYLTAINAAELWAGVALLAEGSRKRTLEASLADLLDRLFGGRLLDFDR
RAARAYAEITRTTTAAGVPLPLADGLIAAIALAHGFAVATRDTTPFRAAGIEVIDPWGDD

Download         Length: 423 bp

>T38751 NZ_AP024563:2417138-2417560 [Allochromatium tepidum]
ATGATAATCCTCGACACCAACGTGGTCTCGGAGCCGCTGCGTCCCCGCGGAAGCGATAAGGTCACGGCCTGGCTCGACGC
CCAGGCGCCGGAGACCCTGTACCTCACTGCGATCAACGCCGCCGAGCTGTGGGCGGGCGTTGCCCTGCTTGCCGAGGGTT
CCCGCAAGCGCACGTTGGAAGCCTCCCTGGCGGACCTGCTCGACCGGCTCTTCGGCGGTCGTCTGCTCGATTTCGATCGT
CGGGCGGCCCGCGCCTATGCCGAGATCACCCGCACGACGACCGCCGCCGGCGTGCCGCTCCCCCTAGCCGATGGGCTGAT
TGCCGCCATTGCCCTCGCCCATGGCTTTGCGGTCGCCACCAGGGACACAACGCCGTTTCGCGCGGCAGGCATCGAGGTGA
TCGACCCCTGGGGCGACGACTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8703.90 Da        Isoelectric Point: 8.8522

>AT38751 WP_213378678.1 NZ_AP024563:2416902-2417141 [Allochromatium tepidum]
MPTVTVRNLPAEVHRALRVRAAAHGRSTEAEIRDILNQAVRSPGGLRLGTELRRYAEQIGGVELPLHRDPSPIEPASFE

Download         Length: 240 bp

>AT38751 NZ_AP024563:2416902-2417141 [Allochromatium tepidum]
ATGCCAACCGTTACGGTCCGCAATCTCCCCGCTGAGGTCCACCGCGCCCTTCGCGTTCGGGCGGCGGCCCATGGCCGCAG
CACAGAGGCCGAGATCCGCGACATCCTGAACCAAGCCGTCCGGTCGCCGGGCGGCCTGCGCTTGGGCACCGAGCTGCGCC
GCTATGCCGAGCAGATCGGCGGTGTCGAACTGCCACTGCACCGTGACCCGTCGCCCATCGAGCCCGCCTCCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References