Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2366182..2366716 Replicon chromosome
Accession NZ_AP024563
Organism Allochromatium tepidum strain NZ

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Atep_RS11420 Protein ID WP_213378638.1
Coordinates 2366182..2366478 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Atep_RS11425 Protein ID WP_213378639.1
Coordinates 2366468..2366716 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Atep_RS11390 (Atep_22130) 2361433..2361885 + 453 WP_213378632.1 ATP synthase subunit C -
Atep_RS11395 (Atep_22140) 2361898..2362272 + 375 WP_213378633.1 V-type ATP synthase subunit F -
Atep_RS11400 (Atep_22150) 2362269..2362916 + 648 WP_213378634.1 V-type ATP synthase subunit E family protein -
Atep_RS11405 (Atep_22160) 2362946..2364742 + 1797 WP_213378635.1 V-type ATP synthase subunit A -
Atep_RS11410 2365256..2365531 + 276 WP_213378636.1 DUF2442 domain-containing protein -
Atep_RS11415 (Atep_22170) 2365649..2366125 + 477 WP_213378637.1 Uma2 family endonuclease -
Atep_RS11420 (Atep_22180) 2366182..2366478 - 297 WP_213378638.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Atep_RS11425 (Atep_22190) 2366468..2366716 - 249 WP_213378639.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Atep_RS11430 (Atep_22200) 2366874..2368256 + 1383 WP_213378640.1 V-type ATP synthase subunit B -
Atep_RS11435 (Atep_22210) 2368253..2368537 + 285 WP_213378641.1 YkgJ family cysteine cluster protein -
Atep_RS11440 (Atep_22220) 2368522..2369142 + 621 WP_213378642.1 V-type ATP synthase subunit D -
Atep_RS11445 (Atep_22230) 2369139..2370719 - 1581 WP_213378643.1 GAF domain-containing protein -
Atep_RS11450 (Atep_22240) 2370781..2371422 + 642 WP_213378644.1 biliverdin-producing heme oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11508.43 Da        Isoelectric Point: 10.4256

>T38750 WP_213378638.1 NZ_AP024563:c2366478-2366182 [Allochromatium tepidum]
MTYELEFKKSALKEWQNLGHTVKEQFKKKLKERLENPHVPAAALSGAKNIYKIKLRRLGYRLVYYVEDKVVTVTVVAVGK
RDRNEIYDIALSRLREQS

Download         Length: 297 bp

>T38750 NZ_AP024563:c2366478-2366182 [Allochromatium tepidum]
ATGACCTATGAACTGGAATTCAAAAAGTCCGCGCTCAAGGAATGGCAAAATTTAGGCCACACCGTAAAAGAGCAATTCAA
GAAAAAACTCAAAGAACGACTTGAAAATCCTCATGTTCCTGCGGCGGCTCTGTCGGGTGCCAAGAACATCTACAAGATCA
AACTCCGCCGACTCGGTTATCGGTTGGTTTACTACGTCGAGGATAAGGTTGTCACTGTGACAGTTGTCGCAGTCGGCAAA
CGTGATCGCAATGAAATTTACGACATTGCGCTTTCTCGGCTGCGCGAACAATCTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9012.54 Da        Isoelectric Point: 4.1225

>AT38750 WP_213378639.1 NZ_AP024563:c2366716-2366468 [Allochromatium tepidum]
MTYQVLTEIAASISELKANPMKVVSSGQGMPIAVLNRNEPAFYCVPAAAYEAMMELIDDVELLKIVKERLDEPAVKVTLD
DL

Download         Length: 249 bp

>AT38750 NZ_AP024563:c2366716-2366468 [Allochromatium tepidum]
ATGACATATCAAGTGCTTACAGAAATCGCGGCCAGTATATCCGAACTCAAGGCCAATCCAATGAAGGTAGTTTCCAGTGG
GCAGGGTATGCCGATCGCCGTTCTGAACCGTAATGAACCCGCTTTTTACTGTGTGCCCGCCGCCGCTTACGAAGCCATGA
TGGAACTGATCGATGATGTCGAACTGTTGAAAATCGTCAAAGAGCGCCTGGATGAGCCAGCTGTCAAGGTGACACTCGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References