Detailed information of TA system TA038748

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 819163..819745
• Replicon: chromosome
• Accession: NZ_AP024563
• Organism: Allochromatium tepidum strain NZ

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: Atep_RS03865
• Protein ID: WP_272876317.1
• Coordinates: 819479..819745 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: Atep_RS03860
• Protein ID: WP_213380356.1
• Coordinates: 819163..819498 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Atep_RS03835 (Atep_07570)	815789..816406	+	618	WP_213380352.1	4Fe-4S dicluster domain-containing protein	-
Atep_RS03840 (Atep_07580)	816410..817369	+	960	WP_213380353.1	polysulfide reductase NrfD	-
Atep_RS03845 (Atep_07590)	817487..818059	+	573	WP_236786449.1	molecular chaperone TorD family protein	-
Atep_RS03850 (Atep_07600)	818049..818609	+	561	WP_213380355.1	[NiFe]-hydrogenase assembly chaperone HybE	-
Atep_RS03855	818679..819138	+	460	Protein_774	tellurium resistance protein TerY	-
Atep_RS03860 (Atep_07620)	819163..819498	-	336	WP_213380356.1	helix-turn-helix transcriptional regulator	Antitoxin
Atep_RS03865 (Atep_07630)	819479..819745	-	267	WP_272876317.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Atep_RS16865	819708..819803	-	96	Protein_777	type II toxin-antitoxin system RelE/ParE family toxin	-
Atep_RS16450 (Atep_07640)	820003..820560	+	558	WP_236786452.1	hypothetical protein	-
Atep_RS16455 (Atep_07650)	820512..820790	+	279	WP_236786454.1	hypothetical protein	-
Atep_RS03875 (Atep_07660)	820797..823190	-	2394	WP_236786457.1	phosphoketolase family protein	-
Atep_RS03880 (Atep_07670)	823330..823467	-	138	WP_176975417.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (34-72)

Antitoxin

• Cro/C1-type helix-turn-helix domain (40-93)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 9772.19 Da
• Isoelectric Point: 10.6999

>T38748 WP_272876317.1 NZ_AP024563:c819745-819479 [Allochromatium tepidum]
MANGTRRPKFSRDSAAPASWRSSKTIPAAPTVPVYTVEFAEAVFVLHCFQKKSKSGISTPKADIELIRARLKVAETIAQE
LRHDNTHH

Nucleotide

• Length: 267 bp

>T38748 NZ_AP024563:c819745-819479 [Allochromatium tepidum]
ATGGCGAACGGCACGCGGCGGCCAAAGTTCTCAAGGGATTCGGCGGCGCCGGCGTCCTGGAGATCGTCGAAGACGATACC
GGCGGCACCTACCGTGCCGGTCTACACCGTCGAATTCGCCGAAGCCGTGTTCGTGCTGCATTGCTTCCAGAAGAAGAGCA
AGAGCGGGATCTCGACGCCAAAAGCAGACATCGAGCTGATTCGCGCCCGGTTGAAAGTGGCCGAAACGATTGCACAGGAA
CTGAGACATGACAACACGCATCATTGA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12145.22 Da
• Isoelectric Point: 9.8318

>AT38748 WP_213380356.1 NZ_AP024563:c819498-819163 [Allochromatium tepidum]
MTTRIIEGIEVETSSGNVFADLELPEAEKLKIKSGLVIEITRAIRRLGLTQEQAGRRMGITQPKVSALLRGQFANLSERK
LMECLTRLGYDIEIKVKPTSAPVGHLTIAAG

Nucleotide

• Length: 336 bp

>AT38748 NZ_AP024563:c819498-819163 [Allochromatium tepidum]
ATGACAACACGCATCATTGAAGGCATCGAGGTCGAAACGAGTTCAGGTAATGTCTTCGCGGATCTTGAACTGCCCGAGGC
CGAAAAGCTTAAGATCAAATCCGGTCTGGTGATCGAGATCACCCGTGCCATCCGCCGACTCGGTCTCACGCAGGAACAAG
CCGGTCGTCGCATGGGAATTACTCAACCCAAGGTATCGGCCCTGCTGCGAGGCCAATTCGCCAACCTGTCCGAGCGCAAA
TTGATGGAATGCCTGACCCGGCTCGGTTACGACATCGAGATCAAGGTCAAACCGACATCCGCACCAGTCGGCCACCTGAC
GATTGCCGCCGGCTGA