Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1996264..1996535 Replicon chromosome
Accession NZ_AP024521
Organism Escherichia coli strain E189

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1996302..1996405 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1996264..1996535 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO00_RS09635 1993421..1994860 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LDO00_RS09640 1994978..1995214 + 237 WP_001295499.1 YebV family protein -
LDO00_RS09645 1995319..1995510 + 192 WP_001296140.1 YebW family protein -
LDO00_RS09650 1995511..1996167 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 1996264..1996535 + 272 - - Antitoxin
- 1996302..1996405 - 104 - - Toxin
LDO00_RS09655 1996563..1996904 - 342 WP_000976472.1 YebY family protein -
LDO00_RS09660 1996917..1997789 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LDO00_RS09665 1997793..1998167 - 375 WP_000204700.1 CopC domain-containing protein YobA -
LDO00_RS09670 1998306..1998536 + 231 WP_000916763.1 DNA polymerase III subunit theta -
LDO00_RS09675 1998638..1999294 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LDO00_RS09680 1999318..1999980 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T38588 NZ_AP024521:c1996405-1996302 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT38588 NZ_AP024521:1996264-1996535 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References