Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1469230..1469781 Replicon chromosome
Accession NZ_AP024515
Organism Nitrosospira sp. NRS527

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KJS40_RS06530 Protein ID WP_213539531.1
Coordinates 1469506..1469781 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KJS40_RS06525 Protein ID WP_244859734.1
Coordinates 1469230..1469502 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJS40_RS06515 (NNRS527_01382) 1466933..1468684 + 1752 WP_213539529.1 hypothetical protein -
KJS40_RS06520 1468830..1468994 + 165 WP_213539530.1 hypothetical protein -
KJS40_RS06525 1469230..1469502 + 273 WP_244859734.1 ribbon-helix-helix domain-containing protein Antitoxin
KJS40_RS06530 1469506..1469781 + 276 WP_213539531.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KJS40_RS06535 (NNRS527_01386) 1470137..1471267 - 1131 WP_213539532.1 TIGR03118 family protein -
KJS40_RS06540 (NNRS527_01387) 1471662..1472594 + 933 WP_213539533.1 NAD-dependent epimerase/dehydratase family protein -
KJS40_RS06545 (NNRS527_01388) 1472708..1473232 + 525 WP_025039653.1 peptide-methionine (R)-S-oxide reductase MsrB -
KJS40_RS06550 (NNRS527_01389) 1473253..1473963 + 711 WP_244859735.1 peptide-methionine (S)-S-oxide reductase MsrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(16-52)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10399.16 Da        Isoelectric Point: 8.4847

>T38547 WP_213539531.1 NZ_AP024515:1469506-1469781 [Nitrosospira sp. NRS527]
MTLKWTVSAERDLARLHALLAPVNSKVAAKVVKQLVAGVQQLLAYPQIGVPLDEFAPRDVRRVIVGDYEVRYEVVDSMIY
ILRLWHAREDQ

Download         Length: 276 bp

>T38547 NZ_AP024515:1469506-1469781 [Nitrosospira sp. NRS527]
ATGACGCTTAAATGGACGGTTAGTGCTGAGCGCGATCTTGCTCGCCTTCACGCCTTACTCGCTCCAGTAAATTCTAAAGT
TGCGGCAAAAGTGGTGAAGCAACTGGTAGCAGGCGTGCAGCAGCTTCTTGCTTATCCGCAGATTGGAGTGCCGCTCGACG
AATTTGCACCCCGTGATGTACGTCGAGTAATTGTGGGGGATTACGAAGTACGTTATGAAGTTGTCGACAGCATGATTTAT
ATCCTTCGCCTCTGGCACGCTCGGGAAGATCAATGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9940.43 Da        Isoelectric Point: 5.5657

>AT38547 WP_244859734.1 NZ_AP024515:1469230-1469502 [Nitrosospira sp. NRS527]
MIEIVSIGLNMNTRVVTAHIPNELAEQIDQLSARLDRPKGWIVKQALTSWVALEVKRHQLTLEGMADVDAGRLVDHASID
AWATSLDKPA

Download         Length: 273 bp

>AT38547 NZ_AP024515:1469230-1469502 [Nitrosospira sp. NRS527]
TTGATTGAGATTGTTTCAATTGGATTAAATATGAATACACGTGTCGTCACCGCTCACATTCCTAATGAACTTGCGGAACA
AATTGATCAACTCTCTGCTCGACTTGATCGTCCCAAGGGCTGGATCGTAAAACAAGCGTTGACCTCTTGGGTTGCTCTTG
AAGTAAAACGCCACCAGCTTACCTTGGAAGGAATGGCAGATGTCGATGCCGGACGCTTGGTGGATCATGCTTCGATTGAT
GCTTGGGCTACGAGCCTCGACAAGCCGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References