Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6588320..6590028 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PproGo58_RS29440 Protein ID WP_102862339.1
Coordinates 6588320..6589198 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PproGo58_RS29445 Protein ID WP_102862340.1
Coordinates 6589195..6590028 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PproGo58_RS29415 6584304..6585155 + 852 WP_102862336.1 ABC transporter ATP-binding protein -
PproGo58_RS29420 6585195..6586196 + 1002 WP_102862337.1 ABC transporter substrate-binding protein -
PproGo58_RS29425 6586226..6587002 + 777 WP_102862338.1 ABC transporter permease -
PproGo58_RS29430 6587002..6587766 + 765 WP_102862533.1 SDR family oxidoreductase -
PproGo58_RS29435 6587779..6588315 + 537 WP_060845001.1 cupin domain-containing protein -
PproGo58_RS29440 6588320..6589198 + 879 WP_102862339.1 alpha/beta hydrolase Toxin
PproGo58_RS29445 6589195..6590028 + 834 WP_102862340.1 IclR family transcriptional regulator Antitoxin
PproGo58_RS29450 6590030..6590827 + 798 WP_207166776.1 SDR family oxidoreductase -
PproGo58_RS29455 6590820..6592502 + 1683 WP_207166777.1 thiamine pyrophosphate-binding protein -
PproGo58_RS29460 6592513..6593316 + 804 WP_207166778.1 aspartate dehydrogenase -
PproGo58_RS29465 6593423..6594919 + 1497 WP_207166779.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30747.46 Da        Isoelectric Point: 8.7608

>T38514 WP_102862339.1 NZ_AP024503:6588320-6589198 [Pseudomonas protegens]
MFPGLSQPAATADLKAQLARDFPQRLVTASGGRQALREGGAGPALVLLHGIGSGAASWLEVAQHLAPKARVIAWDAPGYG
DSSPLEPPAPKAEHYAARLLQMLDALQIEQCVLVGHSLGALPALALARSTQARRVSRLLLISPARGYGAPALAEQGRQVR
QQRLDTLERLGIAGLAEQRSAQMLSPSATPQALAWVRWNMARLNPAGYRQAIELLCGDDLLRHGPPGMPCEVHCGAADRI
TPAEGCRTLAKALGARFNLIADAGHASPVEQPLVVAGRLACAIEESLTGRPL

Download         Length: 879 bp

>T38514 NZ_AP024503:6588320-6589198 [Pseudomonas protegens]
ATGTTCCCAGGCCTCTCTCAACCGGCAGCGACGGCAGACCTGAAAGCCCAGCTGGCCCGGGACTTTCCCCAGCGCCTGGT
GACGGCCAGCGGTGGCCGCCAGGCCCTGCGTGAAGGCGGCGCGGGGCCGGCGCTGGTGCTGCTGCACGGCATCGGCTCCG
GGGCGGCCTCCTGGCTGGAAGTCGCACAGCACCTGGCGCCCAAGGCCCGGGTCATTGCCTGGGACGCGCCCGGCTACGGT
GACTCCAGCCCGCTGGAACCCCCCGCGCCGAAAGCCGAGCACTACGCCGCCCGGCTGCTGCAGATGCTCGATGCGCTGCA
GATCGAGCAATGCGTGCTGGTGGGGCACTCCCTGGGCGCGTTGCCGGCCCTGGCCCTGGCTCGCAGCACCCAGGCCCGGC
GGGTCAGCCGCTTGCTGCTGATCAGCCCGGCCCGGGGCTACGGCGCGCCAGCGCTGGCCGAGCAGGGCCGGCAGGTGCGT
CAACAACGCCTGGACACGCTAGAGCGCCTGGGCATCGCCGGCCTGGCCGAACAGCGCAGCGCCCAGATGCTCTCGCCCTC
CGCCACGCCCCAGGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTGAACCCTGCCGGGTATCGCCAGGCCATCGAGC
TGCTGTGCGGCGACGATCTGCTGCGCCATGGCCCACCCGGCATGCCCTGCGAAGTGCATTGCGGCGCAGCCGACCGCATC
ACCCCGGCCGAGGGTTGCCGGACCCTGGCCAAGGCGCTGGGCGCGCGCTTCAACCTGATCGCCGACGCGGGCCACGCCAG
CCCCGTCGAACAACCGCTGGTGGTGGCGGGCCGCCTGGCCTGCGCCATCGAAGAATCCCTGACAGGTAGACCCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30446.93 Da        Isoelectric Point: 6.9725

>AT38514 WP_102862340.1 NZ_AP024503:6589195-6590028 [Pseudomonas protegens]
MNDADPLKDPQDKYIVPGLERGLLLLCEFSRSNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVSVGTRLPAHATVLGRVLLGDLSLA
ELRELYPEEHLEQHSPSTPNTVMALFDMVQADRQRGFVSGEGFFEPSISTVAAPVRDQSGSIVAALGVTIATAQVGHINY
NELLLQVRRSADELSRLLNYNSAAHNGLPRVTALMRD

Download         Length: 834 bp

>AT38514 NZ_AP024503:6589195-6590028 [Pseudomonas protegens]
ATGAACGACGCCGATCCGCTGAAGGACCCTCAGGACAAATACATAGTCCCGGGCCTGGAACGGGGCCTGTTGCTGCTGTG
CGAGTTCAGCCGCAGCAACCGCACCCTCACTGCCCCGGAGCTGGCCCGGCGCCTGGCCCTGCCGCGCTCGACCATCTTCC
GTCTGCTGACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTGCTGCGC
CTGGGCTTCGAATACCTGGCGTCGCTGGAGCTCACCGAGCTGGGCCAGCCACTGCTGGCGCGGCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTCTACGTGGCCAAGGTTTCGCCACCTTCGGTGTTCTCCA
GCGCGGTCAGTGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTAGGCCGCGTGCTGCTGGGGGATTTGTCCCTGGCC
GAGCTGCGCGAGCTGTACCCGGAGGAACACCTGGAACAGCACTCCCCCAGCACGCCAAACACCGTGATGGCGCTGTTCGA
CATGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGCGGCGAAGGGTTCTTCGAGCCGAGCATTTCCACGGTGGCGGCCC
CGGTGCGTGATCAGAGCGGCAGCATCGTCGCCGCCTTGGGAGTGACCATCGCCACCGCCCAGGTCGGCCACATCAACTAC
AACGAACTGCTGCTGCAGGTACGCCGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACAACAGCGCCGCCCACAACGG
GCTGCCGCGGGTCACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References