Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6588320..6590028 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PproGo58_RS29440 Protein ID WP_102862339.1
Coordinates 6588320..6589198 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PproGo58_RS29445 Protein ID WP_102862340.1
Coordinates 6589195..6590028 (+) Length 278 a.a.

Genomic Context

PproGo58_RS29415PproGo58_RS29420PproGo58_RS29425PproGo58_RS29430PproGo58_RS29435PproGo58_RS29440PproGo58_RS29445PproGo58_RS29450PproGo58_RS29455PproGo58_RS29460PproGo58_RS29465
Location: 6584304..6585155 (852 bp)
Type: Others
Protein ID: WP_102862336.1
Location: 6585195..6586196 (1002 bp)
Type: Others
Protein ID: WP_102862337.1
Location: 6586226..6587002 (777 bp)
Type: Others
Protein ID: WP_102862338.1
Location: 6587002..6587766 (765 bp)
Type: Others
Protein ID: WP_102862533.1
Location: 6587779..6588315 (537 bp)
Type: Others
Protein ID: WP_060845001.1
Location: 6588320..6589198 (879 bp)
Type: Toxin
Protein ID: WP_102862339.1
Location: 6589195..6590028 (834 bp)
Type: Antitoxin
Protein ID: WP_102862340.1
Location: 6590030..6590827 (798 bp)
Type: Others
Protein ID: WP_207166776.1
Location: 6590820..6592502 (1683 bp)
Type: Others
Protein ID: WP_207166777.1
Location: 6592513..6593316 (804 bp)
Type: Others
Protein ID: WP_207166778.1
Location: 6593423..6594919 (1497 bp)
Type: Others
Protein ID: WP_207166779.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PproGo58_RS294156584304..6585155+852WP_102862336.1ABC transporter ATP-binding protein-
PproGo58_RS294206585195..6586196+1002WP_102862337.1ABC transporter substrate-binding protein-
PproGo58_RS294256586226..6587002+777WP_102862338.1ABC transporter permease-
PproGo58_RS294306587002..6587766+765WP_102862533.1SDR family oxidoreductase-
PproGo58_RS294356587779..6588315+537WP_060845001.1cupin domain-containing protein-
PproGo58_RS294406588320..6589198+879WP_102862339.1alpha/beta hydrolaseToxin
PproGo58_RS294456589195..6590028+834WP_102862340.1IclR family transcriptional regulatorAntitoxin
PproGo58_RS294506590030..6590827+798WP_207166776.1SDR family oxidoreductase-
PproGo58_RS294556590820..6592502+1683WP_207166777.1thiamine pyrophosphate-binding protein-
PproGo58_RS294606592513..6593316+804WP_207166778.1aspartate dehydrogenase-
PproGo58_RS294656593423..6594919+1497WP_207166779.1aldehyde dehydrogenase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30747.46 Da        Isoelectric Point: 8.7608

>T38514 WP_102862339.1 NZ_AP024503:6588320-6589198 [Pseudomonas protegens]
MFPGLSQPAATADLKAQLARDFPQRLVTASGGRQALREGGAGPALVLLHGIGSGAASWLEVAQHLAPKARVIAWDAPGYG
DSSPLEPPAPKAEHYAARLLQMLDALQIEQCVLVGHSLGALPALALARSTQARRVSRLLLISPARGYGAPALAEQGRQVR
QQRLDTLERLGIAGLAEQRSAQMLSPSATPQALAWVRWNMARLNPAGYRQAIELLCGDDLLRHGPPGMPCEVHCGAADRI
TPAEGCRTLAKALGARFNLIADAGHASPVEQPLVVAGRLACAIEESLTGRPL

Download         Length: 879 bp

>T38514 NZ_AP024503:6588320-6589198 [Pseudomonas protegens]
ATGTTCCCAGGCCTCTCTCAACCGGCAGCGACGGCAGACCTGAAAGCCCAGCTGGCCCGGGACTTTCCCCAGCGCCTGGT
GACGGCCAGCGGTGGCCGCCAGGCCCTGCGTGAAGGCGGCGCGGGGCCGGCGCTGGTGCTGCTGCACGGCATCGGCTCCG
GGGCGGCCTCCTGGCTGGAAGTCGCACAGCACCTGGCGCCCAAGGCCCGGGTCATTGCCTGGGACGCGCCCGGCTACGGT
GACTCCAGCCCGCTGGAACCCCCCGCGCCGAAAGCCGAGCACTACGCCGCCCGGCTGCTGCAGATGCTCGATGCGCTGCA
GATCGAGCAATGCGTGCTGGTGGGGCACTCCCTGGGCGCGTTGCCGGCCCTGGCCCTGGCTCGCAGCACCCAGGCCCGGC
GGGTCAGCCGCTTGCTGCTGATCAGCCCGGCCCGGGGCTACGGCGCGCCAGCGCTGGCCGAGCAGGGCCGGCAGGTGCGT
CAACAACGCCTGGACACGCTAGAGCGCCTGGGCATCGCCGGCCTGGCCGAACAGCGCAGCGCCCAGATGCTCTCGCCCTC
CGCCACGCCCCAGGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTGAACCCTGCCGGGTATCGCCAGGCCATCGAGC
TGCTGTGCGGCGACGATCTGCTGCGCCATGGCCCACCCGGCATGCCCTGCGAAGTGCATTGCGGCGCAGCCGACCGCATC
ACCCCGGCCGAGGGTTGCCGGACCCTGGCCAAGGCGCTGGGCGCGCGCTTCAACCTGATCGCCGACGCGGGCCACGCCAG
CCCCGTCGAACAACCGCTGGTGGTGGCGGGCCGCCTGGCCTGCGCCATCGAAGAATCCCTGACAGGTAGACCCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30446.93 Da        Isoelectric Point: 6.9725

>AT38514 WP_102862340.1 NZ_AP024503:6589195-6590028 [Pseudomonas protegens]
MNDADPLKDPQDKYIVPGLERGLLLLCEFSRSNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVSVGTRLPAHATVLGRVLLGDLSLA
ELRELYPEEHLEQHSPSTPNTVMALFDMVQADRQRGFVSGEGFFEPSISTVAAPVRDQSGSIVAALGVTIATAQVGHINY
NELLLQVRRSADELSRLLNYNSAAHNGLPRVTALMRD

Download         Length: 834 bp

>AT38514 NZ_AP024503:6589195-6590028 [Pseudomonas protegens]
ATGAACGACGCCGATCCGCTGAAGGACCCTCAGGACAAATACATAGTCCCGGGCCTGGAACGGGGCCTGTTGCTGCTGTG
CGAGTTCAGCCGCAGCAACCGCACCCTCACTGCCCCGGAGCTGGCCCGGCGCCTGGCCCTGCCGCGCTCGACCATCTTCC
GTCTGCTGACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAATGAATACCGCCTGGGCATGTCGGTGCTGCGC
CTGGGCTTCGAATACCTGGCGTCGCTGGAGCTCACCGAGCTGGGCCAGCCACTGCTGGCGCGGCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGTCGCTCGATCGTCTACGTGGCCAAGGTTTCGCCACCTTCGGTGTTCTCCA
GCGCGGTCAGTGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTAGGCCGCGTGCTGCTGGGGGATTTGTCCCTGGCC
GAGCTGCGCGAGCTGTACCCGGAGGAACACCTGGAACAGCACTCCCCCAGCACGCCAAACACCGTGATGGCGCTGTTCGA
CATGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGCGGCGAAGGGTTCTTCGAGCCGAGCATTTCCACGGTGGCGGCCC
CGGTGCGTGATCAGAGCGGCAGCATCGTCGCCGCCTTGGGAGTGACCATCGCCACCGCCCAGGTCGGCCACATCAACTAC
AACGAACTGCTGCTGCAGGTACGCCGCAGCGCCGACGAGCTGTCGCGCCTGCTCAACTACAACAGCGCCGCCCACAACGG
GCTGCCGCGGGTCACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References