Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 4034692..4035347 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PproGo58_RS17735 Protein ID WP_102864928.1
Coordinates 4034692..4034871 (+) Length 60 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PproGo58_RS17740 Protein ID WP_102864927.1
Coordinates 4034922..4035347 (+) Length 142 a.a.

Genomic Context

PproGo58_RS17705PproGo58_RS17730PproGo58_RS17735PproGo58_RS17740PproGo58_RS17710PproGo58_RS17715PproGo58_RS17720PproGo58_RS17725PproGo58_RS17745PproGo58_RS17750PproGo58_RS17755PproGo58_RS17760
Location: 4029923..4030198 (276 bp)
Type: Others
Protein ID: WP_011061856.1
Location: 4034336..4034602 (267 bp)
Type: Others
Protein ID: WP_207166114.1
Location: 4034692..4034871 (180 bp)
Type: Toxin
Protein ID: WP_102864928.1
Location: 4034922..4035347 (426 bp)
Type: Antitoxin
Protein ID: WP_102864927.1
Location: 4030284..4031201 (918 bp)
Type: Others
Protein ID: WP_102864933.1
Location: 4031319..4032536 (1218 bp)
Type: Others
Protein ID: WP_110653569.1
Location: 4032584..4033348 (765 bp)
Type: Others
Protein ID: WP_207166113.1
Location: 4033514..4033903 (390 bp)
Type: Others
Protein ID: WP_102864930.1
Location: 4035419..4035964 (546 bp)
Type: Others
Protein ID: WP_146036435.1
Location: 4036155..4037588 (1434 bp)
Type: Others
Protein ID: WP_102864925.1
Location: 4037766..4038548 (783 bp)
Type: Others
Protein ID: WP_146036434.1
Location: 4038685..4039509 (825 bp)
Type: Others
Protein ID: WP_102864923.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PproGo58_RS177054029923..4030198+276WP_011061856.1peptidylprolyl isomerase-
PproGo58_RS177104030284..4031201-918WP_102864933.1sugar kinase-
PproGo58_RS177154031319..4032536-1218WP_110653569.1amino acid deaminase-
PproGo58_RS177204032584..4033348-765WP_207166113.1helix-turn-helix domain-containing protein-
PproGo58_RS177254033514..4033903-390WP_102864930.1RidA family protein-
PproGo58_RS177304034336..4034602+267WP_207166114.1hypothetical protein-
PproGo58_RS177354034692..4034871+180WP_102864928.1type II toxin-antitoxin system HicA family toxinToxin
PproGo58_RS177404034922..4035347+426WP_102864927.1transcriptional regulatorAntitoxin
PproGo58_RS177454035419..4035964-546WP_146036435.1hypothetical protein-
PproGo58_RS177504036155..4037588-1434WP_102864925.1RtcB family protein-
PproGo58_RS177554037766..4038548-783WP_146036434.1hypothetical protein-
PproGo58_RS177604038685..4039509-825WP_102864923.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6659.70 Da        Isoelectric Point: 11.1475

>T38511 WP_102864928.1 NZ_AP024503:4034692-4034871 [Pseudomonas protegens]
MKFSEFRRWLKAQGVVFEAGKGSHFKVKAPNGNQTTFADHGSKEMPEPTRKAIIRQLGL

Download         Length: 180 bp

>T38511 NZ_AP024503:4034692-4034871 [Pseudomonas protegens]
ATGAAATTCAGCGAATTCAGACGATGGTTGAAAGCTCAAGGCGTGGTCTTCGAGGCCGGTAAAGGCAGCCACTTCAAAGT
TAAGGCCCCAAACGGCAACCAGACCACCTTCGCGGATCACGGCAGCAAGGAAATGCCCGAACCCACCCGCAAGGCAATCA
TCAGGCAATTGGGGCTCTAG

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 15699.05 Da        Isoelectric Point: 4.9375

>AT38511 WP_102864927.1 NZ_AP024503:4034922-4035347 [Pseudomonas protegens]
MYDYALRFEQDRAPGLAVFCRDLPELNSFGDDPEHAINQAIDALETTLSLYVDQRRAIPPASAPLPGEQVIHLPMVTVAK
IALWNTMMERDMRKADLCRLLGIHQAQGDRLVDFLHSSKMEQLENALAALGKRLAVSVEAA

Download         Length: 426 bp

>AT38511 NZ_AP024503:4034922-4035347 [Pseudomonas protegens]
ATGTACGACTACGCCCTTCGCTTCGAGCAAGACCGTGCACCGGGACTGGCGGTCTTCTGCCGCGATCTGCCCGAACTCAA
TAGCTTTGGCGATGATCCTGAGCACGCCATCAACCAGGCCATCGACGCGCTCGAAACCACTCTGTCCCTTTACGTCGACC
AGCGCCGCGCCATTCCCCCGGCCTCCGCGCCGCTACCAGGGGAACAGGTCATTCATTTGCCAATGGTGACCGTGGCCAAG
ATAGCGCTGTGGAACACGATGATGGAGCGGGACATGCGCAAGGCCGATCTATGCCGACTGCTCGGAATCCACCAGGCCCA
GGGAGATCGCCTAGTGGACTTTCTACACAGCTCCAAAATGGAACAGCTGGAAAATGCCCTGGCAGCCCTAGGTAAACGTC
TTGCAGTATCAGTGGAGGCGGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References