38510

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2883860..2885115 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PproGo58_RS13155 Protein ID WP_207167709.1
Coordinates 2884543..2885115 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PproGo58_RS13150 Protein ID WP_060843387.1
Coordinates 2883860..2884417 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PproGo58_RS13125 2878952..2879233 - 282 WP_207167700.1 type II toxin-antitoxin system ParD family antitoxin -
PproGo58_RS13130 2879342..2879962 - 621 WP_207167702.1 LysE family transporter -
PproGo58_RS13135 2880203..2880790 - 588 WP_207167704.1 inclusion body family protein -
PproGo58_RS13140 2881150..2882346 + 1197 WP_207167706.1 PrpF protein -
PproGo58_RS13145 2883329..2883670 - 342 WP_102864516.1 low molecular weight protein tyrosine phosphatase family protein -
PproGo58_RS13150 2883860..2884417 + 558 WP_060843387.1 helix-turn-helix domain-containing protein Antitoxin
PproGo58_RS13155 2884543..2885115 + 573 WP_207167709.1 HD domain-containing protein Toxin
PproGo58_RS13160 2885373..2887553 + 2181 WP_207167711.1 catalase/peroxidase HPI -
PproGo58_RS13165 2887762..2888220 + 459 WP_207167713.1 hypothetical protein -
PproGo58_RS13170 2888412..2888840 - 429 WP_125063949.1 hypothetical protein -
PproGo58_RS13175 2889063..2889326 + 264 WP_102864520.1 hypothetical protein -
PproGo58_RS13180 2889323..2889517 + 195 WP_207167715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2878952..2896531 17579


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-47)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21601.14 Da        Isoelectric Point: 4.7436

>T38510 WP_207167709.1 NZ_AP024503:2884543-2885115 [Pseudomonas protegens]
MTPELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQYLARSLDAPARQRLLELWDEYEGAASTEARTVKALDKLETLLQHTQGQNPADFDYGFNLDY
GRRYTDASPLFQALRQQIDADTRRRLDAQD

Download         Length: 573 bp

>T38510 NZ_AP024503:2884543-2885115 [Pseudomonas protegens]
ATGACCCCCGAACTTCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAAGCCATCCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAACAGGAACGCGACGATCTGCAATACCTCGCCCGGTCCCTGGACGC
CCCGGCCCGCCAGCGCCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCACCGAGGCGCGCACGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGATTTCGACTACGGCTTCAACCTCGATTAC
GGCCGCCGCTACACCGATGCCAGCCCGTTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCGGCGCCGCCTCGA
CGCCCAGGACTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20416.37 Da        Isoelectric Point: 7.4189

>AT38510 WP_060843387.1 NZ_AP024503:2883860-2884417 [Pseudomonas protegens]
MSAALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEHLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAAQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT38510 NZ_AP024503:2883860-2884417 [Pseudomonas protegens]
ATGTCCGCAGCCCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCTGCCGAGCTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAGGCCATGGAGCCGGCGG
AGCGTGCGCGCCTGGAGCACCTGCTGGCGGCCAACCTCAGCGCCGCTGCCGATCAGGCCCTGGCGCGGCTGGTGAATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGCGCAGTTCGG
CGTGCCCTTGAGCGAGCTGCTGGGCCAATCGCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTGCTGGCGCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References