Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 2766708..2767338 | Replicon | chromosome |
| Accession | NZ_AP024503 | ||
| Organism | Pseudomonas protegens strain Go58 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | PproGo58_RS12590 | Protein ID | WP_108543126.1 |
| Coordinates | 2767159..2767338 (-) | Length | 60 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | PproGo58_RS12585 | Protein ID | WP_102864418.1 |
| Coordinates | 2766708..2767115 (-) | Length | 136 a.a. |
Genomic Context
Location: 2763448..2764503 (1056 bp)
Type: Others
Protein ID: WP_207167628.1
Type: Others
Protein ID: WP_207167628.1
Location: 2764515..2764964 (450 bp)
Type: Others
Protein ID: WP_207168039.1
Type: Others
Protein ID: WP_207168039.1
Location: 2765148..2765420 (273 bp)
Type: Others
Protein ID: WP_207167630.1
Type: Others
Protein ID: WP_207167630.1
Location: 2766708..2767115 (408 bp)
Type: Antitoxin
Protein ID: WP_102864418.1
Type: Antitoxin
Protein ID: WP_102864418.1
Location: 2767159..2767338 (180 bp)
Type: Toxin
Protein ID: WP_108543126.1
Type: Toxin
Protein ID: WP_108543126.1
Location: 2767467..2768888 (1422 bp)
Type: Others
Protein ID: WP_207167632.1
Type: Others
Protein ID: WP_207167632.1
Location: 2768872..2770038 (1167 bp)
Type: Others
Protein ID: WP_207167634.1
Type: Others
Protein ID: WP_207167634.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PproGo58_RS12570 | 2763448..2764503 | + | 1056 | WP_207167628.1 | ABC transporter substrate-binding protein | - |
| PproGo58_RS12575 | 2764515..2764964 | + | 450 | WP_207168039.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| PproGo58_RS12580 | 2765148..2765420 | - | 273 | WP_207167630.1 | hypothetical protein | - |
| PproGo58_RS12585 | 2766708..2767115 | - | 408 | WP_102864418.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| PproGo58_RS12590 | 2767159..2767338 | - | 180 | WP_108543126.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| PproGo58_RS12595 | 2767467..2768888 | - | 1422 | WP_207167632.1 | efflux transporter outer membrane subunit | - |
| PproGo58_RS12600 | 2768872..2770038 | - | 1167 | WP_207167634.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6685.92 Da Isoelectric Point: 11.1799
>T38509 WP_108543126.1 NZ_AP024503:c2767338-2767159 [Pseudomonas protegens]
VNIRQLIAQIEADGWYLVRVKGSHHHFKHPTKPGLVTIPHPKKDLLAKTVSSILKQARL
VNIRQLIAQIEADGWYLVRVKGSHHHFKHPTKPGLVTIPHPKKDLLAKTVSSILKQARL
Download Length: 180 bp
>T38509 NZ_AP024503:c2767338-2767159 [Pseudomonas protegens]
GTGAACATCCGGCAACTCATCGCCCAGATCGAAGCAGATGGTTGGTATCTGGTCAGGGTCAAGGGCAGTCACCACCACTT
CAAACACCCAACCAAGCCAGGCCTGGTCACCATTCCCCATCCCAAAAAAGATCTACTGGCCAAAACGGTAAGCAGCATAT
TGAAACAAGCCCGGCTCTAA
GTGAACATCCGGCAACTCATCGCCCAGATCGAAGCAGATGGTTGGTATCTGGTCAGGGTCAAGGGCAGTCACCACCACTT
CAAACACCCAACCAAGCCAGGCCTGGTCACCATTCCCCATCCCAAAAAAGATCTACTGGCCAAAACGGTAAGCAGCATAT
TGAAACAAGCCCGGCTCTAA
Antitoxin
Download Length: 136 a.a. Molecular weight: 14752.81 Da Isoelectric Point: 4.5801
>AT38509 WP_102864418.1 NZ_AP024503:c2767115-2766708 [Pseudomonas protegens]
MLYPIAILPGDDQHAWGVEVPDIPGCFSAGDDLDDAMAMAREAIEGHLELLAEEGAAIPTARTVTLHAANPQYQGCTWAV
IDIDITRYMGKAEKLNITLPGYLLNRIDEYVKHHPEQKSRSGFLAQAALRVLQGV
MLYPIAILPGDDQHAWGVEVPDIPGCFSAGDDLDDAMAMAREAIEGHLELLAEEGAAIPTARTVTLHAANPQYQGCTWAV
IDIDITRYMGKAEKLNITLPGYLLNRIDEYVKHHPEQKSRSGFLAQAALRVLQGV
Download Length: 408 bp
>AT38509 NZ_AP024503:c2767115-2766708 [Pseudomonas protegens]
ATGCTCTATCCCATTGCCATTCTCCCCGGTGACGACCAACACGCCTGGGGTGTGGAAGTACCCGATATTCCTGGCTGCTT
CTCCGCCGGCGACGACCTCGACGACGCCATGGCCATGGCCCGCGAAGCCATCGAAGGCCACCTGGAATTACTGGCCGAAG
AAGGAGCAGCCATTCCCACAGCACGCACAGTGACCCTCCACGCCGCCAATCCCCAGTATCAAGGCTGCACTTGGGCCGTG
ATTGATATCGACATCACTCGCTACATGGGCAAGGCGGAAAAACTCAACATCACGCTGCCGGGCTATTTGCTGAATCGAAT
TGATGAATATGTGAAACATCATCCGGAACAGAAAAGCCGATCGGGCTTTTTGGCTCAGGCCGCGTTGAGGGTCTTGCAGG
GCGTTTGA
ATGCTCTATCCCATTGCCATTCTCCCCGGTGACGACCAACACGCCTGGGGTGTGGAAGTACCCGATATTCCTGGCTGCTT
CTCCGCCGGCGACGACCTCGACGACGCCATGGCCATGGCCCGCGAAGCCATCGAAGGCCACCTGGAATTACTGGCCGAAG
AAGGAGCAGCCATTCCCACAGCACGCACAGTGACCCTCCACGCCGCCAATCCCCAGTATCAAGGCTGCACTTGGGCCGTG
ATTGATATCGACATCACTCGCTACATGGGCAAGGCGGAAAAACTCAACATCACGCTGCCGGGCTATTTGCTGAATCGAAT
TGATGAATATGTGAAACATCATCCGGAACAGAAAAGCCGATCGGGCTTTTTGGCTCAGGCCGCGTTGAGGGTCTTGCAGG
GCGTTTGA