Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1541279..1541792 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PproGo58_RS06990 Protein ID WP_110595048.1
Coordinates 1541279..1541563 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PproGo58_RS06995 Protein ID WP_092320301.1
Coordinates 1541553..1541792 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PproGo58_RS06965 1536284..1537171 - 888 WP_102861554.1 dihydrodipicolinate synthase family protein -
PproGo58_RS06970 1537203..1537985 - 783 WP_102878683.1 aldolase -
PproGo58_RS06975 1538147..1538689 + 543 WP_102861556.1 XRE family transcriptional regulator -
PproGo58_RS06980 1538902..1539921 - 1020 WP_102861727.1 DUF4917 family protein -
PproGo58_RS06985 1540079..1541227 + 1149 WP_102861557.1 L-threonine dehydrogenase -
PproGo58_RS06990 1541279..1541563 - 285 WP_110595048.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PproGo58_RS06995 1541553..1541792 - 240 WP_092320301.1 ribbon-helix-helix protein, CopG family Antitoxin
PproGo58_RS07000 1541993..1542730 + 738 WP_207167203.1 hypothetical protein -
PproGo58_RS07005 1542741..1543472 + 732 WP_102861559.1 hypothetical protein -
PproGo58_RS07010 1543476..1543892 + 417 WP_102861560.1 fosfomycin resistance glutathione transferase -
PproGo58_RS07015 1544019..1544657 + 639 WP_102861561.1 LysE family translocator -
PproGo58_RS07020 1544766..1546115 + 1350 WP_207167204.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11040.72 Da        Isoelectric Point: 11.8691

>T38507 WP_110595048.1 NZ_AP024503:c1541563-1541279 [Pseudomonas protegens]
MRIEWLRSALNNLDAEARHIAQDDPRAAGEFVRALLISIEQLARFPSSGREGRLPGTREWVVPGWPYLIPYRVRGDRLQI
LRIFHTRRQPPARW

Download         Length: 285 bp

>T38507 NZ_AP024503:c1541563-1541279 [Pseudomonas protegens]
ATGCGCATTGAATGGCTACGCAGCGCCCTGAACAACCTGGACGCTGAGGCCCGTCATATCGCCCAGGACGATCCCCGGGC
CGCCGGGGAATTTGTCAGGGCGCTGTTGATCAGTATCGAGCAACTGGCCCGGTTCCCCTCAAGTGGCCGCGAAGGCCGCC
TGCCCGGCACCCGGGAATGGGTAGTGCCGGGCTGGCCTTACCTAATTCCCTACCGGGTGCGCGGGGACCGGCTACAGATT
CTGCGAATTTTCCATACCCGCCGTCAGCCCCCGGCACGTTGGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8604.71 Da        Isoelectric Point: 4.3085

>AT38507 WP_092320301.1 NZ_AP024503:c1541792-1541553 [Pseudomonas protegens]
MSIMSLRLPDELAETLALLAKATGRSKSFLAVDALREYLAREAWQIEEIQKALNEADAGDFASAEEVAAIAGKWTDNAH

Download         Length: 240 bp

>AT38507 NZ_AP024503:c1541792-1541553 [Pseudomonas protegens]
ATGTCCATCATGTCCCTGCGCTTGCCCGATGAACTTGCTGAAACTCTGGCCCTGCTGGCAAAAGCCACCGGACGCAGCAA
GTCGTTTCTCGCCGTGGACGCCCTGCGTGAATACCTGGCGCGGGAAGCCTGGCAAATCGAGGAAATCCAGAAGGCCCTGA
ACGAGGCCGACGCAGGTGACTTCGCCAGTGCCGAAGAAGTGGCGGCCATCGCCGGCAAGTGGACCGACAATGCGCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References