38505

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 382960..383565 Replicon chromosome
Accession NZ_AP024503
Organism Pseudomonas protegens strain Go58

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PproGo58_RS01765 Protein ID WP_207166934.1
Coordinates 382960..383250 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PproGo58_RS01770 Protein ID WP_207166935.1
Coordinates 383260..383565 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PproGo58_RS01735 378075..379013 + 939 WP_207166931.1 formimidoylglutamase -
PproGo58_RS01740 379066..380274 + 1209 WP_102863055.1 sodium/glutamate symporter -
PproGo58_RS01745 380275..381270 - 996 WP_207166932.1 alpha/beta fold hydrolase -
PproGo58_RS01750 381319..381648 - 330 WP_102862724.1 hypothetical protein -
PproGo58_RS01755 381771..382091 + 321 WP_102862725.1 isochorismate lyase -
PproGo58_RS01760 382206..382787 + 582 WP_207166933.1 hypothetical protein -
PproGo58_RS01765 382960..383250 + 291 WP_207166934.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PproGo58_RS01770 383260..383565 + 306 WP_207166935.1 putative addiction module antidote protein Antitoxin
PproGo58_RS01775 383790..384830 + 1041 WP_207166936.1 EamA family transporter -
PproGo58_RS01780 385126..385404 + 279 WP_102863056.1 hypothetical protein -
PproGo58_RS01785 385491..386567 - 1077 Protein_348 DUF1016 family protein -
PproGo58_RS01795 386977..387249 - 273 WP_047301095.1 oxidative damage protection protein -
PproGo58_RS01800 387246..388313 - 1068 WP_207166937.1 A/G-specific adenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10979.74 Da        Isoelectric Point: 10.3337

>T38505 WP_207166934.1 NZ_AP024503:382960-383250 [Pseudomonas protegens]
MHTLIQTERYSQWFARLRDARAQARIKARLRRVELGVLGDCKPVGEGVSELRIDYGPGYRLYFVQRGYEVIVLLAGGDKA
TQAADMRIAIRLSREL

Download         Length: 291 bp

>T38505 NZ_AP024503:382960-383250 [Pseudomonas protegens]
ATGCACACGCTTATTCAGACAGAGCGTTATAGCCAGTGGTTTGCCAGGCTGAGGGACGCTCGGGCACAGGCTCGGATCAA
AGCTCGACTTCGTCGAGTGGAGTTGGGGGTTTTGGGTGACTGCAAGCCGGTGGGTGAGGGGGTATCTGAGTTGCGGATAG
ATTATGGGCCGGGTTATCGACTGTATTTCGTGCAGCGCGGCTATGAAGTGATTGTTCTGCTGGCCGGTGGTGACAAGGCG
ACTCAGGCCGCTGATATGAGGATTGCCATCAGGCTGTCCCGTGAGCTCTAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10853.56 Da        Isoelectric Point: 5.0877

>AT38505 WP_207166935.1 NZ_AP024503:383260-383565 [Pseudomonas protegens]
MTKIKLSKWDVVDHLKTEQDMALYLEACLEENDPVLLAAALGDIARARGMSQLARDTGLTREGLYKALSADGNPSLATIM
KVMGALGIKLHAEVGTVQQDG

Download         Length: 306 bp

>AT38505 NZ_AP024503:383260-383565 [Pseudomonas protegens]
ATGACCAAGATAAAACTGAGCAAGTGGGATGTAGTCGATCACTTGAAGACTGAACAGGACATGGCTCTTTACCTTGAAGC
CTGTCTGGAGGAGAACGATCCCGTGCTGCTGGCTGCGGCCTTGGGCGATATCGCGCGAGCGCGTGGGATGTCGCAGCTAG
CCCGAGATACTGGCCTGACTCGCGAGGGGCTTTACAAGGCCCTATCAGCTGATGGCAACCCCAGTTTGGCGACCATCATG
AAGGTCATGGGCGCATTGGGTATAAAGCTGCATGCTGAGGTCGGTACGGTGCAGCAAGACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References