Detailed information of TA system TA038477

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RHH(antitoxin)
• Location: 3086192..3086730
• Replicon: chromosome
• Accession: NZ_AP024488
• Organism: Desulfoluna limicola strain ASN36

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: L6434_RS11780
• Protein ID: WP_236893093.1
• Coordinates: 3086192..3086488 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: L6434_RS11785
• Protein ID: WP_236893094.1
• Coordinates: 3086494..3086730 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L6434_RS11770 (DSLASN_24410)	3081720..3083711	-	1992	WP_236893165.1	ankyrin repeat domain-containing protein	-
L6434_RS11775 (DSLASN_24420)	3084676..3085953	+	1278	WP_236893092.1	Hsp70 family protein	-
L6434_RS11780 (DSLASN_24430)	3086192..3086488	-	297	WP_236893093.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L6434_RS11785 (DSLASN_24440)	3086494..3086730	-	237	WP_236893094.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
L6434_RS11795 (DSLASN_24450)	3087376..3089721	-	2346	WP_236893095.1	methyl-accepting chemotaxis protein	-
L6434_RS11800 (DSLASN_24460)	3090520..3091407	-	888	WP_236893096.1	heterodisulfide reductase-related iron-sulfur binding cluster	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-91)

Antitoxin

• Antitoxin ParD (1-76)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11529.24 Da
• Isoelectric Point: 10.4999

>T38477 WP_236893093.1 NZ_AP024488:c3086488-3086192 [Desulfoluna limicola]
MSSFRLTAKALEDFKSMGRHTQKKWGRDQRNTYLAKLNYSFHLLADQPFSGTASDNIREGYRVYHVGRHLIFYRLAPSHI
EIIRILHEKMDAQIHLKG

Nucleotide

• Length: 297 bp

>T38477 NZ_AP024488:c3086488-3086192 [Desulfoluna limicola]
ATGTCCTCATTTCGACTGACTGCAAAGGCCCTTGAAGATTTTAAGTCCATGGGTCGCCATACTCAGAAAAAATGGGGCCG
TGATCAACGAAATACCTACCTTGCCAAGCTTAATTATAGCTTCCACTTACTGGCTGATCAGCCATTTTCAGGGACCGCCT
CCGATAACATTCGAGAGGGCTACCGGGTCTATCATGTCGGCCGCCATTTGATATTTTACCGTTTGGCACCGTCCCACATT
GAAATTATCCGTATCCTGCATGAAAAAATGGATGCCCAAATACACCTGAAAGGGTGA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8870.96 Da
• Isoelectric Point: 4.5792

>AT38477 WP_236893094.1 NZ_AP024488:c3086730-3086494 [Desulfoluna limicola]
MQKNTSVTLGEHFEKFIAHQIKCGRYASASEVIRDGLRVLEERELKLKALQSALKEGEGSGFVEYSLERVIEDLDEED

Nucleotide

• Length: 237 bp

>AT38477 NZ_AP024488:c3086730-3086494 [Desulfoluna limicola]
ATGCAAAAAAATACAAGTGTCACGTTGGGTGAGCATTTTGAAAAGTTTATCGCCCATCAGATTAAATGTGGTCGATACGC
ATCCGCAAGCGAAGTCATTCGGGATGGATTGCGGGTTCTTGAAGAGCGGGAATTAAAGTTGAAGGCTTTGCAGAGCGCGT
TGAAAGAGGGAGAGGGTAGTGGCTTTGTAGAGTATTCACTGGAAAGGGTGATTGAAGATCTTGATGAAGAGGATTGA