Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3086192..3086730 Replicon chromosome
Accession NZ_AP024488
Organism Desulfoluna limicola strain ASN36

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag L6434_RS11780 Protein ID WP_236893093.1
Coordinates 3086192..3086488 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag L6434_RS11785 Protein ID WP_236893094.1
Coordinates 3086494..3086730 (-) Length 79 a.a.

Genomic Context


L6434_RS11775L6434_RS11770L6434_RS11780L6434_RS11785L6434_RS11795L6434_RS11800
Location: 3084676..3085953 (1278 bp)
Type: Others
Protein ID: WP_236893092.1
Location: 3081720..3083711 (1992 bp)
Type: Others
Protein ID: WP_236893165.1
Location: 3086192..3086488 (297 bp)
Type: Toxin
Protein ID: WP_236893093.1
Location: 3086494..3086730 (237 bp)
Type: Antitoxin
Protein ID: WP_236893094.1
Location: 3087376..3089721 (2346 bp)
Type: Others
Protein ID: WP_236893095.1
Location: 3090520..3091407 (888 bp)
Type: Others
Protein ID: WP_236893096.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
L6434_RS11770 (DSLASN_24410)3081720..3083711-1992WP_236893165.1ankyrin repeat domain-containing protein-
L6434_RS11775 (DSLASN_24420)3084676..3085953+1278WP_236893092.1Hsp70 family protein-
L6434_RS11780 (DSLASN_24430)3086192..3086488-297WP_236893093.1type II toxin-antitoxin system RelE/ParE family toxinToxin
L6434_RS11785 (DSLASN_24440)3086494..3086730-237WP_236893094.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
L6434_RS11795 (DSLASN_24450)3087376..3089721-2346WP_236893095.1methyl-accepting chemotaxis protein-
L6434_RS11800 (DSLASN_24460)3090520..3091407-888WP_236893096.1heterodisulfide reductase-related iron-sulfur binding cluster-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-91)

Antitoxin

(1-76)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11529.24 Da        Isoelectric Point: 10.4999

>T38477 WP_236893093.1 NZ_AP024488:c3086488-3086192 [Desulfoluna limicola]
MSSFRLTAKALEDFKSMGRHTQKKWGRDQRNTYLAKLNYSFHLLADQPFSGTASDNIREGYRVYHVGRHLIFYRLAPSHI
EIIRILHEKMDAQIHLKG

Download         Length: 297 bp

>T38477 NZ_AP024488:c3086488-3086192 [Desulfoluna limicola]
ATGTCCTCATTTCGACTGACTGCAAAGGCCCTTGAAGATTTTAAGTCCATGGGTCGCCATACTCAGAAAAAATGGGGCCG
TGATCAACGAAATACCTACCTTGCCAAGCTTAATTATAGCTTCCACTTACTGGCTGATCAGCCATTTTCAGGGACCGCCT
CCGATAACATTCGAGAGGGCTACCGGGTCTATCATGTCGGCCGCCATTTGATATTTTACCGTTTGGCACCGTCCCACATT
GAAATTATCCGTATCCTGCATGAAAAAATGGATGCCCAAATACACCTGAAAGGGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8870.96 Da        Isoelectric Point: 4.5792

>AT38477 WP_236893094.1 NZ_AP024488:c3086730-3086494 [Desulfoluna limicola]
MQKNTSVTLGEHFEKFIAHQIKCGRYASASEVIRDGLRVLEERELKLKALQSALKEGEGSGFVEYSLERVIEDLDEED

Download         Length: 237 bp

>AT38477 NZ_AP024488:c3086730-3086494 [Desulfoluna limicola]
ATGCAAAAAAATACAAGTGTCACGTTGGGTGAGCATTTTGAAAAGTTTATCGCCCATCAGATTAAATGTGGTCGATACGC
ATCCGCAAGCGAAGTCATTCGGGATGGATTGCGGGTTCTTGAAGAGCGGGAATTAAAGTTGAAGGCTTTGCAGAGCGCGT
TGAAAGAGGGAGAGGGTAGTGGCTTTGTAGAGTATTCACTGGAAAGGGTGATTGAAGATCTTGATGAAGAGGATTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References